Lembar kerja Farmakologi dengan jawaban

What does pharmacokinetics describe?

1. AHow drugs are manufactured and packaged
2. BWhat the body does to a drug: absorption, distribution, metabolism and excretion
3. CHow the price of a drug is set
4. DWhat a drug does to the body: its effects, receptors and mechanisms of action

Sertralin, suatu antidepresan, meningkatkan kadar neurotransmiter apa di sinaps?

1. AGABA
2. BAsetilkolin
3. CDopamin
4. DSerotonin

Which signs are typical of hypoglycaemia?

1. AThirst, frequent urination and warm, dry, flushed skin
2. BSweating, shakiness, a fast heart rate and confusion
3. CFruity breath with deep, rapid breathing
4. DA slow pulse, constipation and weight gain

Seorang pasien mengalami gangguan ginjal berat. Suatu obat terutama diekskresikan tanpa berubah melalui urine. Apa penyesuaian yang lazim?

1. AMenaikkan dosis untuk mengimbangi penyerapan yang buruk
2. BMenurunkan dosis atau memperpanjang interval pemberian
3. CMemberikan obat secara oral alih-alih intravena
4. DTidak perlu perubahan, karena hati mengambil alih

An IV site is cool, swollen and pale, and the infusion is running slowly. What should the nurse do?

1. AIncrease the infusion rate to push through and clear the blockage
2. BFlush the cannula forcefully with saline
3. CApply a tight bandage over the site
4. DStop the infusion, remove the cannula and elevate the limb

Agonis parsial diberikan bersama agonis penuh dosis tinggi. Apa yang terjadi pada responsnya?

1. ARespons berlipat dua, karena kedua obat mengaktifkan reseptor
2. BRespons tetap persis sama seperti pada dosis tinggi agonis penuh saja
3. CRespons naik melebihi maksimum agonis penuh
4. DRespons turun, karena agonis parsial bersaing memperebutkan reseptor

A patient taking long-term hydroxychloroquine for lupus is advised to have regular eye examinations. Why?

1. AThe drug raises pressure inside the eye
2. BThe drug stains the cornea blue
3. CThe drug causes cataracts within a few weeks of starting
4. DThe drug can cause retinal toxicity that may be permanent

A malnourished patient with low serum albumin shows nystagmus and unsteady gait. Her total phenytoin level is within range. What is the most likely explanation?

1. AMore phenytoin is unbound when albumin is low, so free levels rise
2. BLow albumin speeds up phenytoin metabolism
3. CThe total level is high, but the laboratory is wrong
4. DLow albumin makes phenytoin bind more tightly, so the drug is less active