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Nama: ____________________ Tanggal: ____________
1.Mudah
Baclofen is used mainly to treat:
ABacterial infections of the skin
BAcid reflux and heartburn
CHigh blood pressure in pregnancy and pre-eclampsia
DMuscle spasticity, for example in multiple sclerosis
2.Mudah
Which drug class is first-line for stopping a seizure in status epilepticus?
ABenzodiazepines, such as IV lorazepam
BBeta blockers, such as IV metoprolol
CAntihistamines, such as IV chlorphenamine
DOpioids, such as IV morphine
3.Mudah
Giving a patient immunoglobulin after exposure to an infection provides which type of immunity?
AActive immunity
BInnate immunity
CHerd immunity
DPassive immunity
4.Sedang
A patient starting sulfasalazine should be told about which harmless effect?
AGreen colouring of the sweat
BWhite spots on the nails
COrange-yellow colouring of the urine
DBlue colouring of the tongue and gums
5.Sedang
A patient takes cholestyramine. How should other oral medicines be timed?
ATake them 1 hour before or several hours after cholestyramine
BMix them into the cholestyramine drink so they are taken together
CTake them all at the same time as cholestyramine
DTiming does not matter, as cholestyramine is not absorbed
6.Sedang
Faktor mana yang meningkatkan risiko toksisitas litium?
AMinum air lebih banyak
BMengonsumsi dosis bersama makanan
CDiet tinggi garam
DDehidrasi
7.Sulit
Untuk obat dengan eliminasi orde pertama, menggandakan dosis (tanpa mengubah interval) akan:
ATidak mengubah kadar keadaan tunak tetapi menjadikan waktu untuk mencapainya separuhnya
BMenggandakan kadar keadaan tunak tetapi tidak mengubah waktu untuk mencapainya
CMenggandakan waktu paruh
DMemangkas setengah waktu untuk mencapai keadaan tunak
8.Sulit
Why is clavulanic acid combined with amoxicillin (co-amoxiclav)?
AIt inhibits beta-lactamase enzymes that would destroy amoxicillin
BIt slows the kidney excretion of amoxicillin
CIt makes amoxicillin cross the blood–brain barrier more easily
DIt reduces the risk of penicillin allergy
Kunci jawaban
1. D · Muscle spasticity, for example in multiple sclerosis
2. A · Benzodiazepines, such as IV lorazepam
3. D · Passive immunity
4. C · Orange-yellow colouring of the urine
5. A · Take them 1 hour before or several hours after cholestyramine
6. D · Dehidrasi
7. B · Menggandakan kadar keadaan tunak tetapi tidak mengubah waktu untuk mencapainya
8. A · It inhibits beta-lactamase enzymes that would destroy amoxicillin
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