Lembar kerja Farmakologi dengan jawaban

Sertralin, suatu antidepresan, meningkatkan kadar neurotransmiter apa di sinaps?

1. ADopamin
2. BGABA
3. CSerotonin
4. DAsetilkolin

Statin seperti atorvastatin menurunkan kolesterol dengan menghambat enzim apa?

1. ALipoprotein lipase
2. BSiklooksigenase
3. CHMG-CoA reduktase
4. DEnzim pengubah angiotensin

Apa yang digambarkan oleh "efikasi" suatu obat?

1. ADosis yang diperlukan untuk menghasilkan separuh efek
2. BBagian dosis yang terikat pada protein plasma
3. CEfek maksimum yang dapat dihasilkan obat
4. DKecepatan penyerapan obat

Which description fits tardive dyskinesia?

1. AA sudden painful spasm of the neck muscles and upward rolling of the eyes within days of the first dose
2. BA low white cell count with sore throat and fever
3. CInvoluntary movements of the lips, tongue and face after long-term antipsychotic use
4. DHigh fever with lead-pipe rigidity and confusion

Pasien yang menggunakan penghambat MAO generasi lama diperingatkan tentang makanan kaya tiramin. Apa yang dapat terjadi?

1. AGagal ginjal mendadak
2. BKrisis hipertensi
3. CRuam alergi
4. DHipoglikemia berat

How does sucralfate help a peptic ulcer heal?

1. AIt kills Helicobacter pylori directly
2. BIt neutralises acid by releasing bicarbonate
3. CIt blocks histamine H2 receptors in the stomach
4. DIt forms a protective coating over the ulcer base

A patient on simvastatin is prescribed gemfibrozil. What is the main concern?

1. ALoss of all lipid-lowering effect
2. BA much higher risk of myopathy and rhabdomyolysis
3. CA sharp rise in LDL cholesterol and triglycerides
4. DSevere hypoglycaemia

Why are tetracyclines usually avoided in pregnancy and in young children (under 8 years in US guidance, under 12 years in the UK)?

1. AThey cause severe hearing loss in children
2. BThey bind to growing teeth and bone and stain the teeth permanently
3. CThey block the action of growth hormone and stunt the child's growth
4. DThey cause grey baby syndrome in infants