Lembar kerja Farmakologi dengan jawaban

With patient-controlled analgesia (PCA), who should press the button to give a dose?

1. AThe nursing assistant at set times
2. BOnly the patient
3. CA family member when the patient is asleep
4. DAny visitor who thinks the patient is in pain

Why is folinic acid (leucovorin) given after high-dose methotrexate?

1. ATo prevent nausea and vomiting after the methotrexate
2. BTo make methotrexate act faster on the tumour
3. CTo treat an allergic reaction to methotrexate
4. DTo protect normal cells from methotrexate toxicity

Apa yang dimaksud dengan nama generik suatu obat?

1. ANama yang dipilih perusahaan untuk pemasaran
2. BNama nonpaten (non-proprietary) zat aktifnya
3. CRumus kimia yang tercetak di kemasan
4. DNama apotek yang membuatnya

Why is testing for HLA-B*15:02 recommended before carbamazepine in people of some Asian ancestries?

1. AThis gene variant makes carbamazepine ineffective
2. BThis gene variant speeds up the kidney excretion of carbamazepine
3. CIt greatly raises the risk of Stevens–Johnson syndrome
4. DThis gene variant causes carbamazepine to raise blood glucose

Why are benzodiazepines used with great caution in older people?

1. AThey cause permanent hearing loss in older people
2. BThey raise the risk of confusion, falls and fractures
3. CThey are not absorbed from the gut after age 65
4. DThey cause severe high blood pressure in older people

Which side effects are most common when starting gabapentin?

1. ADrowsiness and dizziness
2. BHair loss and weight loss
3. CInsomnia and agitation
4. DCough and runny nose

A man on long-term testosterone therapy has a rising haematocrit. Why is this important?

1. AA high haematocrit shows that the testosterone is not being absorbed
2. BIt means the testosterone dose is too low
3. CTestosterone raises red cell production, increasing clot risk
4. DIt is a sign of liver failure caused by testosterone

Antagonis nonkompetitif (ireversibel) mengubah kurva dosis-respons dengan:

1. AMembuat kurva lebih curam tanpa perubahan lain
2. BMenurunkan respons maksimum
3. CMenggeser kurva ke kiri
4. DMenggeser kurva ke kanan dengan maksimum yang sama