Lembar kerja Farmakologi dengan jawaban

Finasteride is used in benign prostatic hyperplasia because it:

1. AKills bacteria in the prostate
2. BRelaxes smooth muscle in the prostate within hours of the first dose
3. CInhibits 5-alpha reductase and slowly shrinks the prostate
4. DIncreases testosterone production

Apa itu indeks terapeutik?

1. ARasio antara dosis toksik dan dosis efektif
2. BPersentase dosis oral yang mencapai sirkulasi sistemik
3. CJumlah dosis per hari
4. DWaktu untuk mencapai keadaan tunak

Dobutamine is mainly used to:

1. ADissolve clots in the coronary arteries
2. BSlow the heart rate in fast atrial fibrillation with low blood pressure
3. CIncrease heart contractility in cardiogenic shock or acute heart failure
4. DTreat high blood pressure at home

During an amphotericin B infusion, the patient has fever, chills and shaking. What is the most likely explanation?

1. ASevere hypoglycaemia caused by the drug
2. BA common infusion reaction to amphotericin B
3. CA sign that the drug has been given into an artery
4. DA sign that the fungal infection is cured

A patient takes theophylline for COPD. Which advice is most important?

1. AAvoid potassium-rich foods such as bananas
2. BTake extra doses when short of breath
3. CDrink plenty of grapefruit juice each morning to improve absorption
4. DLimit coffee, tea and cola, because caffeine adds to the side effects

A patient takes low-dose weekly methotrexate for rheumatoid arthritis. Which monitoring is needed?

1. ARegular blood count, liver and kidney function tests
2. BDaily blood glucose checks
3. CMonthly hearing tests
4. DWeekly INR checks and a monthly ECG to check the heart rhythm

A patient with asthma starts timolol eye drops for glaucoma and soon becomes wheezy. What is the most likely explanation?

1. AThe wheeze is unrelated to the eye drops
2. BThe eye drops contain an allergen that causes hay fever and asthma
3. CTimolol activates histamine receptors in the lungs
4. DTimolol is absorbed and blocks beta-2 receptors in the airways

Which finding most favours serotonin syndrome over neuroleptic malignant syndrome?

1. AA very high creatine kinase
2. BRecent start of an antipsychotic drug
3. CSlow onset over days with lead-pipe rigidity
4. DRapid onset with hyperreflexia and clonus