Lembar kerja Farmakologi dengan jawaban

Celecoxib selectively inhibits which enzyme?

1. ACyclo-oxygenase-2 (COX-2)
2. BCyclo-oxygenase-1 (COX-1)
3. CPhospholipase A2
4. DLipoxygenase

Mannitol is an osmotic diuretic used mainly to:

1. APrevent blood clots
2. BRaise serum potassium
3. CReduce raised intracranial pressure
4. DTreat high blood pressure long term

What is the normal serum potassium range in adults?

1. A135–145 mmol/L
2. B6,0–7,5 mmol/L
3. C3,5–5,0 mmol/L
4. D1,5–2,5 mmol/L

A patient is starting olanzapine. Which monitoring is most important over the following months?

1. AHearing tests and vision tests every month
2. BPeak expiratory flow
3. CINR and platelet count
4. DWeight, blood glucose and blood lipids

A 19-year-old starts an SSRI for depression. Which is most important for the nurse to monitor during the first weeks?

1. ABlood glucose before every meal and at bedtime
2. BNew or worsening suicidal thoughts or agitation
3. CDaily bowel movements only
4. DHearing loss and tinnitus

A patient given haloperidol develops a sudden painful twisting of the neck and the eyes roll upward. Which drug is usually given?

1. ADantrolene by mouth to relax the twisted neck muscles
2. BAn anticholinergic such as benzatropine (benztropine)
3. CA second dose of haloperidol
4. DNaloxone

A patient taking long-term hydroxychloroquine for lupus is advised to have regular eye examinations. Why?

1. AThe drug stains the cornea blue
2. BThe drug can cause retinal toxicity that may be permanent
3. CThe drug raises pressure inside the eye
4. DThe drug causes cataracts within a few weeks of starting

A patient with severe chronic hyponatraemia receives hypertonic saline. Why is the rate of correction strictly limited?

1. AHypertonic saline is toxic to the liver at high rates
2. BRaising sodium too fast causes severe hypokalaemia and cardiac arrest
3. CFast correction causes immediate kidney failure
4. DRaising sodium too fast can cause osmotic demyelination in the brain