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Nama: ____________________ Tanggal: ____________
1.Mudah
Celecoxib selectively inhibits which enzyme?
ACyclo-oxygenase-2 (COX-2)
BCyclo-oxygenase-1 (COX-1)
CLipoxygenase
DPhospholipase A2
2.Mudah
Giving a patient immunoglobulin after exposure to an infection provides which type of immunity?
APassive immunity
BHerd immunity
CActive immunity
DInnate immunity
3.Mudah
Tamoxifen is used mainly to treat:
AType 2 diabetes
BOsteoarthritis
COestrogen receptor-positive breast cancer
DProstate enlargement and prostate cancer in older men
4.Sedang
Bagaimana heparin menghasilkan efek antikoagulannya?
AHeparin memblokir sintesis faktor pembekuan yang bergantung pada vitamin K di hati
BHeparin meningkatkan kerja antitrombin, yang menginaktifkan trombin dan faktor Xa
CHeparin menghambat COX-1 trombosit secara ireversibel
DHeparin menguraikan fibrin dalam bekuan yang sudah ada
5.Sedang
Jenis diuretik apa yang bekerja di lengkung asendens tebal ansa Henle?
ADiuretik hemat kalium
BDiuretik kuat (loop) seperti furosemid
CDiuretik osmotik
DDiuretik tiazid
6.Sedang
Bethanechol may be used for non-obstructive urinary retention. How does it work?
AIt stimulates muscarinic receptors and contracts the bladder muscle
BIt increases urine production in the kidney
CIt blocks muscarinic receptors and relaxes the bladder wall muscle
DIt shrinks the prostate gland
7.Sulit
A patient on warfarin also takes ginkgo and high-dose garlic supplements and is having minor surgery next week. What should the nurse do?
ATell the surgical team, as the supplements can increase bleeding
BAdvise stopping warfarin without telling anyone
CIgnore the supplements, as natural products are safe with warfarin
DAdvise taking extra supplements to improve healing
8.Sulit
Probenesid pernah digunakan untuk menaikkan kadar penisilin plasma. Bagaimana caranya?
AProbenesid memblokir sekresi tubulus penisilin di ginjal
BProbenesid meningkatkan penyerapan penisilin dari usus halus
CProbenesid menghambat metabolisme penisilin di hati
DProbenesid menggeser penisilin dari protein plasma
Kunci jawaban
1. A · Cyclo-oxygenase-2 (COX-2)
2. A · Passive immunity
3. C · Oestrogen receptor-positive breast cancer
4. B · Heparin meningkatkan kerja antitrombin, yang menginaktifkan trombin dan faktor Xa
5. B · Diuretik kuat (loop) seperti furosemid
6. A · It stimulates muscarinic receptors and contracts the bladder muscle
7. A · Tell the surgical team, as the supplements can increase bleeding
8. A · Probenesid memblokir sekresi tubulus penisilin di ginjal
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