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Nama: ____________________ Tanggal: ____________
1.Mudah
On the WHO analgesic ladder, which drugs form the first step?
ALocal anaesthetic nerve blocks for all patients
BNon-opioids such as paracetamol and NSAIDs
CStrong opioids such as morphine given intravenously
DWeak opioids such as codeine or tramadol, used on their own
2.Mudah
Obat mana yang membalikkan efek heparin?
AProtamin sulfat
BFlumazenil
CNalokson
DVitamin K
3.Mudah
Filgrastim, a granulocyte colony-stimulating factor (G-CSF), is given to:
ALower the white cell count in leukaemia
BIncrease the production of platelets
CIncrease the production of neutrophils
DStop bleeding from wounds
4.Sedang
Why should a patient rinse the mouth after using an inhaled corticosteroid?
ATo reduce the risk of oral thrush (candidiasis) and hoarseness
BTo stop the drug being absorbed too quickly into the blood
CTo make the drug work faster in the lungs
DTo prevent a fall in blood glucose
5.Sedang
Bagaimana neostigmin meningkatkan kekuatan otot pada miastenia gravis?
ANeostigmin memblokir autoantibodi terhadap reseptor
BNeostigmin langsung merangsang reseptor muskarinik di otot
CNeostigmin meningkatkan jumlah reseptor asetilkolin di sambungan neuromuskular
DNeostigmin menghambat asetilkolinesterase sehingga lebih banyak asetilkolin mencapai reseptor
6.Sedang
A patient taking levodopa finds that the drug works poorly after large meals. Which advice is most appropriate?
AAvoid taking doses at the same time as high-protein meals
BTake the drug only at bedtime
CDouble the dose after each meal
DTake every dose with a large glass of milk and a protein snack
7.Sulit
A patient on digoxin is started on amiodarone. What change should the nurse expect?
ANo interaction is expected
BDigoxin levels fall sharply, so the digoxin dose is doubled
CDigoxin levels rise, so the digoxin dose is often reduced
DAmiodarone levels fall to zero
8.Sulit
Pada overdosis aspirin, urine dapat dibuat basa dengan natrium bikarbonat. Mengapa hal ini meningkatkan ekskresi salisilat?
AUrine basa meningkatkan filtrasi glomerulus
BBikarbonat mengikat salisilat dan membuatnya tidak aktif
CBikarbonat mempercepat metabolisme salisilat di hati menjadi bentuk tidak aktif
DLebih banyak salisilat terionisasi di tubulus, sehingga lebih sedikit yang direabsorpsi
Kunci jawaban
1. B · Non-opioids such as paracetamol and NSAIDs
2. A · Protamin sulfat
3. C · Increase the production of neutrophils
4. A · To reduce the risk of oral thrush (candidiasis) and hoarseness
5. D · Neostigmin menghambat asetilkolinesterase sehingga lebih banyak asetilkolin mencapai reseptor
6. A · Avoid taking doses at the same time as high-protein meals
7. C · Digoxin levels rise, so the digoxin dose is often reduced
8. D · Lebih banyak salisilat terionisasi di tubulus, sehingga lebih sedikit yang direabsorpsi
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