Lembar kerja Farmakologi dengan jawaban

Apa arti "waktu paruh" suatu obat?

1. AWaktu agar konsentrasi plasma turun menjadi setengahnya
2. BWaktu sampai obat mulai bekerja
3. CSetengah dari lama obat berada di tubuh
4. DWaktu agar setengah dosis diserap dari usus

Organ mana yang mengekskresikan sebagian besar obat larut air dan metabolitnya?

1. AParu-paru
2. BGinjal
3. CHati
4. DKulit

With patient-controlled analgesia (PCA), who should press the button to give a dose?

1. AThe nursing assistant at set times
2. BA family member when the patient is asleep
3. CAny visitor who thinks the patient is in pain
4. DOnly the patient

Why should loperamide usually be avoided in bloody diarrhoea with fever?

1. ASlowing the gut may keep bacteria and toxins in the bowel longer
2. BLoperamide makes the bleeding worse by blocking platelets
3. CLoperamide is an antibiotic that causes resistance
4. DLoperamide causes severe hypertension when there is an infection

During an amphotericin B infusion, the patient has fever, chills and shaking. What is the most likely explanation?

1. AA common infusion reaction to amphotericin B
2. BA sign that the drug has been given into an artery
3. CSevere hypoglycaemia caused by the drug
4. DA sign that the fungal infection is cured

A patient with suspected sepsis has blood cultures ordered and a first antibiotic dose due. What should the nurse do?

1. AWait for the culture results before giving any antibiotic
2. BTake the blood cultures first, then give the antibiotic at once
3. CGive the antibiotic first, then take blood cultures the next day
4. DGive the antibiotic only if the temperature is above 40 °C (104 °F)

Before starting rituximab, patients are tested for hepatitis B. Why?

1. AHepatitis B infection makes rituximab completely ineffective
2. BRituximab can reactivate hepatitis B and cause liver failure
3. CRituximab is made from the hepatitis B virus
4. DRituximab is a vaccine against hepatitis B

A patient on simvastatin is prescribed gemfibrozil. What is the main concern?

1. AA much higher risk of myopathy and rhabdomyolysis
2. BA sharp rise in LDL cholesterol and triglycerides
3. CLoss of all lipid-lowering effect
4. DSevere hypoglycaemia