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Nama: ____________________ Tanggal: ____________
1.Mudah
Apa yang digambarkan oleh "efikasi" suatu obat?
ABagian dosis yang terikat pada protein plasma
BEfek maksimum yang dapat dihasilkan obat
CDosis yang diperlukan untuk menghasilkan separuh efek
DKecepatan penyerapan obat
2.Mudah
Where is a sublingual tablet placed?
ABetween the cheek and the gum
BUnder the tongue
COn top of the tongue, then chewed
DIn the stomach, swallowed with water
3.Mudah
Which drug is the antidote for paracetamol (acetaminophen) overdose?
AFlumazenil
BAcetylcysteine
CVitamin K
DNaloxone
4.Sedang
A patient receives lactulose for hepatic encephalopathy. Which finding shows that it is working?
ABetter alertness and orientation, with two to three soft stools a day
BHigher blood ammonia with improved appetite
CNo bowel movement for three days, with less confusion than before
DTen watery stools a day and a low serum potassium
5.Sedang
How should a hyoscine (scopolamine) patch for motion sickness be used?
ASwallow it if no water is available
BApply it behind the ear several hours before travel
CApply it to the chest only after the vomiting has started
DCut it in half for children without advice
6.Sedang
After several years of levodopa treatment, which problem is common?
ASevere hypoglycaemia after each dose
BDyskinesias and "on–off" fluctuations in response
CComplete and permanent loss of all Parkinson's symptoms
DPermanent hearing loss
7.Sulit
Seorang pria berusia 80 tahun dengan pembesaran prostat mulai mengonsumsi oksibutinin untuk kandung kemih overaktif. Ia menjadi bingung dan tidak dapat berkemih. Apa penjelasan yang paling mungkin?
AReaksi alergi terhadap obat
BToksisitas opioid
CEfek samping antikolinergik
DSindrom serotonin
8.Sulit
A patient with heart failure starts taking naproxen regularly for back pain. Why is this a concern?
ANSAIDs increase heart contractility too much
BNSAIDs cause salt and water retention and can worsen heart failure
CNSAIDs block the absorption of furosemide completely
DNSAIDs lower potassium, which makes digoxin and diuretics fail
Kunci jawaban
1. B · Efek maksimum yang dapat dihasilkan obat
2. B · Under the tongue
3. B · Acetylcysteine
4. A · Better alertness and orientation, with two to three soft stools a day
5. B · Apply it behind the ear several hours before travel
6. B · Dyskinesias and "on–off" fluctuations in response
7. C · Efek samping antikolinergik
8. B · NSAIDs cause salt and water retention and can worsen heart failure
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