Scheda di esercizi di Farmacologia con soluzioni

Filgrastim, a granulocyte colony-stimulating factor (G-CSF), is given to:

1. AStop bleeding from wounds
2. BIncrease the production of platelets
3. CIncrease the production of neutrophils
4. DLower the white cell count in leukaemia

How do local anaesthetics such as lidocaine block pain?

1. AThey block prostaglandin synthesis at the injury site
2. BThey activate opioid receptors in the spinal cord
3. CThey enhance the action of GABA in the brain and spinal cord
4. DThey block voltage-gated sodium channels in nerve membranes

Methylphenidate, used in ADHD, belongs to which class?

1. ABenzodiazepines
2. BCentral nervous system stimulants
3. COpioid analgesics
4. DAntipsychotics (dopamine blockers)

Which adverse effect of doxorubicin requires monitoring of heart function?

1. APericarditis caused by infection
2. BSevere hypertension during the infusion itself
3. CCumulative heart muscle damage leading to heart failure
4. DRapid rise in cholesterol

Why are benzodiazepines used with great caution in older people?

1. AThey are not absorbed from the gut after age 65
2. BThey raise the risk of confusion, falls and fractures
3. CThey cause permanent hearing loss in older people
4. DThey cause severe high blood pressure in older people

Come produce l'eparina il suo effetto anticoagulante?

1. AInibisce in modo irreversibile la COX-1 piastrinica
2. BDegrada la fibrina dei coaguli già formati
3. CBlocca la sintesi epatica dei fattori della coagulazione vitamina K-dipendenti
4. DPotenzia l'antitrombina, che inattiva la trombina e il fattore Xa

A woman with epilepsy who takes an antiepileptic drug plans to become pregnant. Which advice is standard?

1. AAvoid folic acid because it lowers drug levels
2. BNo change is needed, as antiepileptics carry no risk in pregnancy
3. CTake folic acid before conception and seek specialist review of her medication
4. DStop all antiepileptic drugs straight away as soon as she stops contraception

A drug is ordered at 5 micrograms/kg/min for an 80 kg patient. The infusion contains 1,600 micrograms per mL. What rate in mL/h is needed?

1. A25 mL/h
2. B150 mL/h
3. C15 mL/h
4. D4 mL/h