1.やさしい
What is enzyme induction?
- AA drug speeds up liver enzymes, so other drugs are broken down faster
- BA drug is converted into an enzyme in the body
- CA drug blocks liver enzymes, so other drugs build up in the blood
- DA drug causes an allergic reaction to enzymes
2.やさしい
Which of these drugs has a narrow therapeutic index?
- ALoratadine
- BOmeprazole
- CLithium
- DAmoxicillin
3.やさしい
How is pernicious anaemia usually treated?
- AWith folic acid alone
- BWith vitamin B12 injections, usually for life
- CWith blood transfusions every month
- DWith oral iron tablets for three months, then stopping
4.ふつう
Why is simvastatin traditionally taken in the evening?
- AIt is inactivated by sunlight during the day
- BIt must be taken with the largest meal of the day
- CIt is short-acting, and cholesterol synthesis peaks at night
- DIt causes too much drowsiness to be taken in the morning
5.ふつう
How does sucralfate help a peptic ulcer heal?
- AIt forms a protective coating over the ulcer base
- BIt kills Helicobacter pylori directly
- CIt blocks histamine H2 receptors in the stomach
- DIt neutralises acid by releasing bicarbonate
6.ふつう
A child weighing 20 kg is prescribed a drug at 15 mg/kg per dose. What is the dose?
- A300 mg
- B35 mg
- C3000 mg
- D150 mg
7.むずかしい
妊娠中に服用すると神経管閉鎖障害と発達の問題のリスクが最も高いことでよく知られている抗てんかん薬はどれですか?
- Aレベチラセタム
- Bラモトリギン
- Cバルプロ酸ナトリウム
- Dガバペンチン
8.むずかしい
A patient receives high-dose IV aciclovir for herpes encephalitis. Which nursing action reduces the main risk to the kidneys?
- AKeep the patient well hydrated and give the infusion slowly
- BGive the infusion as a rapid push
- CRestrict oral and IV fluids to prevent brain swelling
- DGive a loop diuretic before each dose
解答
- 1. A · A drug speeds up liver enzymes, so other drugs are broken down faster
- 2. C · Lithium
- 3. B · With vitamin B12 injections, usually for life
- 4. C · It is short-acting, and cholesterol synthesis peaks at night
- 5. A · It forms a protective coating over the ulcer base
- 6. A · 300 mg
- 7. C · バルプロ酸ナトリウム
- 8. A · Keep the patient well hydrated and give the infusion slowly
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