1.やさしい
What does "polypharmacy" mean?
- AA pharmacy that stocks many different brands of the same drug
- BTaking one drug in several different forms
- CUsing a drug at a very high dose
- DThe use of many medicines at the same time, often five or more
2.やさしい
How does activated charcoal work in poisoning?
- AIt binds (adsorbs) the poison in the gut so less is absorbed
- BIt neutralises acids in the blood
- CIt speeds up liver metabolism of the poison
- DIt makes the patient vomit the poison before it is absorbed
3.やさしい
Which adverse effect can follow long-term use of strong topical corticosteroids?
- AIncreased hair loss on the scalp
- BPermanent darkening of the nails
- CThickening of the skin
- DThinning of the skin
4.ふつう
When does oseltamivir give the most benefit in influenza?
- AWhen started within 48 hours of the first symptoms
- BAt any time, as the timing makes no difference
- COnly after a bacterial pneumonia has developed
- DOnly after symptoms have lasted at least one week
5.ふつう
How is adenosine given for supraventricular tachycardia?
- AAs a rapid IV push followed by a fast saline flush
- BAs a tablet under the tongue
- CAs an intramuscular injection into the outer thigh muscle
- DAs a slow infusion over one hour
6.ふつう
A patient starting niacin (nicotinic acid) complains of flushing and warmth after doses. Which advice may reduce this?
- ATake the niacin with a hot drink so that it dissolves and acts faster
- BDouble the dose to build tolerance faster
- CTake it on an empty stomach in a hot bath
- DTake aspirin 30 minutes before the niacin, if the prescriber agrees
7.むずかしい
Lithium taken in the first trimester of pregnancy has been linked to which type of birth defect?
- ACleft lip and palate only
- BHeart malformations, such as Ebstein's anomaly
- CLimb defects similar to thalidomide
- DNeural tube defects such as spina bifida
8.むずかしい
A drug is ordered at 5 micrograms/kg/min for an 80 kg patient. The infusion contains 1,600 micrograms per mL. What rate in mL/h is needed?
- A15 mL/h
- B25 mL/h
- C150 mL/h
- D4 mL/h
解答
- 1. D · The use of many medicines at the same time, often five or more
- 2. A · It binds (adsorbs) the poison in the gut so less is absorbed
- 3. D · Thinning of the skin
- 4. A · When started within 48 hours of the first symptoms
- 5. A · As a rapid IV push followed by a fast saline flush
- 6. D · Take aspirin 30 minutes before the niacin, if the prescriber agrees
- 7. B · Heart malformations, such as Ebstein's anomaly
- 8. A · 15 mL/h
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