1.やさしい
薬の「半減期」とは何を意味しますか?
- A薬が効き始めるまでの時間
- B薬が体内にとどまる時間の半分
- C血漿中濃度が半分に下がるまでの時間
- D投与量の半分が腸から吸収されるまでの時間
2.やさしい
Which vitamin reverses the effect of warfarin?
- AVitamin E
- BVitamin B12
- CVitamin C
- DVitamin K
3.やさしい
Which vasopressor is usually first-line for septic shock that persists after fluids?
- AGlyceryl trinitrate
- BIsoprenaline (isoproterenol)
- CNoradrenaline (norepinephrine)
- DAdenosine
4.ふつう
Which advice helps reduce the most common side effect of varenicline?
- ATake it with alcohol to reduce nausea
- BTake it after food with a full glass of water
- CTake it on an empty stomach at bedtime with a little milk
- DTake double doses in the first week
5.ふつう
A patient with a fentanyl patch is given home-care advice. Which instruction is correct?
- AAvoid heating pads, hot baths and saunas over or near the patch
- BThrow used patches loose into the household bin with the packaging
- CApply each new patch over the same skin area
- DCut the patch in half if the pain is mild
6.ふつう
A woman taking the combined pill should seek care urgently for which symptom?
- ASlight nausea in the first few weeks
- BA painful, swollen calf or sudden chest pain
- CLight spotting between periods early on
- DMild breast tenderness in the first month
7.むずかしい
A patient receiving frequent salbutamol (albuterol) nebulisers develops a fine tremor and a heart rate of 120 per minute. What is the best explanation?
- AThe patient is allergic to salbutamol and needs adrenaline
- BAt high doses it also stimulates beta receptors in skeletal muscle and the heart
- CSalbutamol blocks muscarinic receptors in the heart
- DSalbutamol causes high potassium, which speeds the heart and causes muscle twitching
8.むずかしい
A patient has SIADH with mild hyponatraemia and no neurological symptoms. What is usually the first-line treatment?
- ALarge volumes of IV glucose 5%
- BA rapid bolus of hypertonic saline
- CFluid restriction
- DDesmopressin
解答
- 1. C · 血漿中濃度が半分に下がるまでの時間
- 2. D · Vitamin K
- 3. C · Noradrenaline (norepinephrine)
- 4. B · Take it after food with a full glass of water
- 5. A · Avoid heating pads, hot baths and saunas over or near the patch
- 6. B · A painful, swollen calf or sudden chest pain
- 7. B · At high doses it also stimulates beta receptors in skeletal muscle and the heart
- 8. C · Fluid restriction
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