解答つき薬理学ワークシート

Which of these is an extrapyramidal side effect of antipsychotics?

1. AWeight gain
2. BAkathisia (a feeling of inner restlessness)
3. CDry mouth
4. DAgranulocytosis (a very low neutrophil count)

Celecoxib selectively inhibits which enzyme?

1. APhospholipase A2
2. BCyclo-oxygenase-2 (COX-2)
3. CLipoxygenase
4. DCyclo-oxygenase-1 (COX-1)

インスリンを錠剤ではなく注射で投与するのはなぜですか？

1. A錠剤では放出が遅すぎるから
2. B骨格筋に直接届いたときだけ効くから
3. C腸で消化されてしまうタンパク質だから
4. D胃の粘膜には毒性が強すぎるから

Which drug is used for torsades de pointes?

1. AIntravenous adenosine (rapid push)
2. BIntravenous verapamil
3. COral digoxin
4. DIntravenous magnesium sulfate

Which assessments are most important during a magnesium sulfate infusion?

1. ATemperature and skin colour only
2. BBlood glucose, pupil size and pupil reaction to light
3. CDeep tendon reflexes, respiratory rate and urine output
4. DBowel sounds and appetite

During an infusion of a vesicant chemotherapy drug, the patient reports burning, and the site is swollen. What should the nurse do first?

1. AIncrease the infusion rate to finish quickly
2. BStop the infusion, leave the cannula in and follow the protocol
3. CRemove the cannula at once and massage the area firmly
4. DFlush the line with a large volume of saline

A patient on stable warfarin is prescribed a course of metronidazole. What is the likely effect, and what should the nurse expect?

1. AMetronidazole replaces warfarin, so warfarin is stopped
2. BThe INR stays the same, as these drugs do not interact
3. CThe INR rises, so closer INR monitoring is needed
4. DThe INR falls, so the risk of clotting increases

A patient taking sertraline starts St John's wort for low mood. What is the main concern?

1. AA hypertensive crisis from tyramine
2. BSerotonin syndrome from combined serotonergic effects
3. CSevere low blood pressure from blocked alpha receptors
4. DBleeding from vitamin K deficiency