1.やさしい
Why is vitamin K given to newborn babies?
- ATo prevent neonatal jaundice in the first week
- BTo improve weight gain
- CTo protect against hepatitis B
- DTo prevent vitamin K deficiency bleeding
2.やさしい
With patient-controlled analgesia (PCA), who should press the button to give a dose?
- AOnly the patient
- BAny visitor who thinks the patient is in pain
- CThe nursing assistant at set times
- DA family member when the patient is asleep
3.やさしい
What is a prodrug?
- AA drug that is given before surgery
- BA drug that is inactive until the body converts it into its active form
- CA drug that has passed all clinical trials
- DA drug that prevents or reverses the effect of another drug in the body
4.ふつう
Which antihypertensive class can raise blood glucose and uric acid levels, sometimes triggering gout?
- AACE inhibitors
- BThiazide diuretics
- CAlpha-1 blockers
- DAngiotensin II receptor blockers
5.ふつう
Which adverse effect is a well-known risk of zidovudine?
- AOrange-red colouring of the urine and tears
- BBone marrow suppression, especially anaemia
- CGum overgrowth
- DRed–green colour blindness
6.ふつう
What should the nurse teach a patient about taking levothyroxine?
- ATake it on an empty stomach, 30–60 minutes before breakfast
- BTake it only on days when feeling tired
- CTake it together with the iron tablet to save time
- DTake it with milk at dinner, as calcium protects the stomach lining
7.むずかしい
A patient taking long-term hydroxychloroquine for lupus is advised to have regular eye examinations. Why?
- AThe drug stains the cornea blue
- BThe drug can cause retinal toxicity that may be permanent
- CThe drug raises pressure inside the eye
- DThe drug causes cataracts within a few weeks of starting
8.むずかしい
一次消失の薬で、投与間隔を変えずに投与量を 2 倍にすると:
- A定常状態の濃度は変わらないが、到達までの時間が半分になる
- B定常状態の濃度は 2 倍になるが、到達までの時間は変わらない
- C定常状態に達する時間が半分になる
- D半減期が 2 倍になる
解答
- 1. D · To prevent vitamin K deficiency bleeding
- 2. A · Only the patient
- 3. B · A drug that is inactive until the body converts it into its active form
- 4. B · Thiazide diuretics
- 5. B · Bone marrow suppression, especially anaemia
- 6. A · Take it on an empty stomach, 30–60 minutes before breakfast
- 7. B · The drug can cause retinal toxicity that may be permanent
- 8. B · 定常状態の濃度は 2 倍になるが、到達までの時間は変わらない
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