解答つき薬理学ワークシート

ワルファリンなど、ほとんどの酸性薬物と結合する血漿タンパク質はどれですか？

1. Aフィブリノゲン
2. Bアルブミン
3. Cインスリン
4. Dヘモグロビン

Why do nurses wear chemotherapy-tested gloves and gowns when handling cytotoxic drugs?

1. ABecause cytotoxic drugs are radioactive and give off radiation
2. BTo keep the drugs warm during the infusion
3. CTo protect the drug from light
4. DTo avoid exposure to drugs that may cause cancer or birth defects

What is a "broad-spectrum" antibiotic?

1. AOne that is given only intravenously in hospital
2. BOne that also treats viral and fungal infections
3. COne that is taken for a long time at low dose to prevent any infection
4. DOne that acts against many Gram-positive and Gram-negative bacteria

An Rh-negative mother gives birth to an Rh-positive baby. When is anti-D immunoglobulin usually given?

1. AOnly at the start of the next pregnancy
2. BAt least two weeks after the birth
3. CIt is not needed if the baby is Rh-positive
4. DWithin 72 hours after the birth

Which adverse effects are typical of donepezil?

1. AHair loss and skin pigmentation
2. BDry mouth, constipation and a fast heart rate
3. CNausea, diarrhoea and a slow heart rate
4. DWeight gain and high blood glucose

Which patient should usually not receive a live vaccine?

1. AA patient with mild seasonal allergies
2. BA healthy adult nurse who works on a children's ward
3. CA patient receiving chemotherapy for leukaemia
4. DA healthy 1-year-old child

ワルファリン服用中の患者がリファンピシンを飲み始めました。起こりうる影響は？

1. Aワルファリンがビタミン K に変わる
2. Bワルファリンの代謝が遅れ INR が上がる
3. Cリファンピシンは吸収されないので影響はない
4. Dワルファリンの代謝が速まり INR が下がる

Why is the TPMT enzyme often tested before azathioprine is started?

1. ALow TPMT activity causes toxic levels and marrow suppression
2. BTPMT is needed to absorb azathioprine from the gut
3. CTPMT testing shows whether the patient has tuberculosis
4. DHigh TPMT activity causes an allergic reaction to azathioprine