1.やさしい
What is a prodrug?
- AA drug that is inactive until the body converts it into its active form
- BA drug that has passed all clinical trials
- CA drug that is given before surgery
- DA drug that prevents or reverses the effect of another drug in the body
2.やさしい
Before giving any medication, how should the nurse identify the patient?
- ARead the name on the sign next to the door
- BUse two identifiers, such as full name and date of birth
- CCheck the room and bed number against the medication chart
- DAsk "Are you Mr Jones?" and wait for a nod
3.やさしい
Dextromethorphan is used as:
- AA cough suppressant
- BAn antibiotic for chest infections
- CA nasal decongestant
- DAn expectorant that thins mucus
4.ふつう
A patient with a fentanyl patch is given home-care advice. Which instruction is correct?
- AApply each new patch over the same skin area
- BThrow used patches loose into the household bin with the packaging
- CAvoid heating pads, hot baths and saunas over or near the patch
- DCut the patch in half if the pain is mild
5.ふつう
Why is hypovolaemia corrected with IV fluids before or while starting a vasopressor?
- AVasopressors cannot keep perfusion up if the circulation is under-filled
- BVasopressors cause the patient to retain too much fluid
- CVasopressors only work when they are diluted in large fluid volumes
- DFluids stop the vasopressor causing a fever
6.ふつう
A patient taking levodopa finds that the drug works poorly after large meals. Which advice is most appropriate?
- ATake the drug only at bedtime
- BAvoid taking doses at the same time as high-protein meals
- CTake every dose with a large glass of milk and a protein snack
- DDouble the dose after each meal
7.むずかしい
ある薬の分布容積は 40 L で、バイオアベイラビリティは完全です。目標血漿濃度 2 mg/L を得る負荷量はどれですか?
- A160 mg
- B42 mg
- C20 mg
- D80 mg
8.むずかしい
A patient with Parkinson's disease has nausea. Why should metoclopramide be avoided?
- AIt increases dopamine levels in the brain too much and causes psychosis
- BIt blocks dopamine receptors in the brain and can worsen the parkinsonism
- CIt causes severe diarrhoea in Parkinson's disease
- DIt inhibits the absorption of all oral drugs
解答
- 1. A · A drug that is inactive until the body converts it into its active form
- 2. B · Use two identifiers, such as full name and date of birth
- 3. A · A cough suppressant
- 4. C · Avoid heating pads, hot baths and saunas over or near the patch
- 5. A · Vasopressors cannot keep perfusion up if the circulation is under-filled
- 6. B · Avoid taking doses at the same time as high-protein meals
- 7. D · 80 mg
- 8. B · It blocks dopamine receptors in the brain and can worsen the parkinsonism
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