解答つき薬理学ワークシート

What is enzyme induction?

1. AA drug blocks liver enzymes, so other drugs build up in the blood
2. BA drug speeds up liver enzymes, so other drugs are broken down faster
3. CA drug is converted into an enzyme in the body
4. DA drug causes an allergic reaction to enzymes

What does "polypharmacy" mean?

1. AThe use of many medicines at the same time, often five or more
2. BUsing a drug at a very high dose
3. CA pharmacy that stocks many different brands of the same drug
4. DTaking one drug in several different forms

How is pernicious anaemia usually treated?

1. AWith oral iron tablets for three months, then stopping
2. BWith vitamin B12 injections, usually for life
3. CWith blood transfusions every month
4. DWith folic acid alone

リチウム中毒のリスクを高める要因はどれですか？

1. A塩分の多い食事
2. B脱水
3. C水を多めに飲むこと
4. D食事と一緒に服用すること

Why are patients taking simvastatin often advised to avoid large amounts of grapefruit juice?

1. AGrapefruit blocks cholesterol absorption and causes low cholesterol
2. BGrapefruit speeds up simvastatin breakdown in the liver, so the drug stops working
3. CGrapefruit inhibits CYP3A4 in the gut, raising simvastatin levels and myopathy risk
4. DGrapefruit makes the tablet dissolve in the mouth

Why is a progestogen added to oestrogen in hormone replacement therapy for a woman who still has her uterus?

1. ATo protect against endometrial hyperplasia and cancer
2. BTo prevent breast cancer completely
3. CTo reduce hot flushes much more than oestrogen alone can
4. DTo lower the risk of blood clots to zero

QT 間隔を延長させる薬を複数併用すると、命に関わるどの不整脈のリスクが高まりますか？

1. A1 度房室ブロック
2. B心房細動
3. C洞性頻脈
4. Dトルサード・ド・ポワント

A patient taking dabigatran has a life-threatening bleed. Which specific reversal agent is used?

1. AVitamin K
2. BAndexanet alfa
3. CProtamine sulfate
4. DIdarucizumab