1.やさしい
What is drug synergism?
- ATwo drugs together have a greater effect than the sum of each alone
- BTwo drugs together produce exactly the sum of their separate effects
- CA drug loses its effect after repeated doses
- DOne drug cancels out the effect of another drug
2.やさしい
Which intramuscular site is recommended for infants?
- ADeltoid
- BDorsogluteal (upper outer buttock)
- CVentral forearm
- DVastus lateralis (outer thigh)
3.やさしい
What is the most common side effect of first-generation antihistamines such as diphenhydramine?
- AInsomnia
- BRaised blood pressure
- CDiarrhoea
- DDrowsiness
4.ふつう
A patient starting niacin (nicotinic acid) complains of flushing and warmth after doses. Which advice may reduce this?
- ATake aspirin 30 minutes before the niacin, if the prescriber agrees
- BTake it on an empty stomach in a hot bath
- CTake the niacin with a hot drink so that it dissolves and acts faster
- DDouble the dose to build tolerance faster
5.ふつう
When should a patient take a once-daily proton pump inhibitor such as omeprazole?
- AStraight after a large evening meal
- BWith a glass of milk at bedtime, when acid output is highest
- COnly when heartburn is severe
- DAbout 30–60 minutes before the first meal of the day
6.ふつう
How should oral potassium chloride tablets be taken?
- ALying down straight after the dose
- BOn an empty stomach with only a small sip of water, then lie down
- CWith food and plenty of water, swallowed whole if slow-release
- DCrushed and dissolved under the tongue
7.むずかしい
A postoperative patient using morphine PCA is very drowsy, hard to rouse and has a respiratory rate of 7 per minute. What should the nurse do first?
- AEncourage the patient to press the button only when awake and in pain
- BLet the patient sleep and recheck in one hour
- CReduce the PCA dose and leave the pump running
- DStop the PCA, try to rouse the patient and give naloxone as per protocol
8.むずかしい
A patient has a serum potassium of 7.0 mmol/L (mEq/L) and peaked T waves on the ECG. Which drug is given first to protect the heart?
- AOral sodium polystyrene sulfonate
- BIntravenous furosemide
- COral potassium chloride
- DIntravenous calcium gluconate
解答
- 1. A · Two drugs together have a greater effect than the sum of each alone
- 2. D · Vastus lateralis (outer thigh)
- 3. D · Drowsiness
- 4. A · Take aspirin 30 minutes before the niacin, if the prescriber agrees
- 5. D · About 30–60 minutes before the first meal of the day
- 6. C · With food and plenty of water, swallowed whole if slow-release
- 7. D · Stop the PCA, try to rouse the patient and give naloxone as per protocol
- 8. D · Intravenous calcium gluconate
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