1.やさしい
What is the purpose of "Tall Man" lettering, such as hydrOXYzine and hydrALAZINE?
- ATo show which drugs are for children
- BTo show the brand name of the drug
- CTo reduce confusion between look-alike drug names
- DTo show which drugs are high-alert medications
2.やさしい
Celecoxib selectively inhibits which enzyme?
- APhospholipase A2
- BCyclo-oxygenase-1 (COX-1)
- CCyclo-oxygenase-2 (COX-2)
- DLipoxygenase
3.やさしい
Why are corticosteroids such as betamethasone given to a woman at risk of preterm birth?
- ATo lower the mother's blood glucose
- BTo stop contractions completely
- CTo speed up fetal lung maturity
- DTo prevent infection in the mother
4.ふつう
Why is testing for HLA-B*15:02 recommended before carbamazepine in people of some Asian ancestries?
- AThis gene variant makes carbamazepine ineffective
- BThis gene variant causes carbamazepine to raise blood glucose
- CThis gene variant speeds up the kidney excretion of carbamazepine
- DIt greatly raises the risk of Stevens–Johnson syndrome
5.ふつう
一定間隔で投与した薬が定常状態に達するまで、おおよそどのくらいかかりますか?
- A半減期の 4~5 倍
- B半減期の 10 倍
- C投与量の大きさだけで決まる
- D半減期 1 回分
6.ふつう
グリクラジドなどのスルホニル尿素薬の最も重要な副作用は何ですか?
- A空咳
- B低血糖
- C高カリウム血症
- D乳酸アシドーシス
7.むずかしい
A patient on warfarin is taught about diet. Which statement shows a need for further teaching?
- A"I will tell my dentist that I take warfarin."
- B"I will use a soft toothbrush and an electric razor."
- C"I will stop eating all green vegetables from now on."
- D"I will keep the amount of green leafy vegetables I eat about the same each week."
8.むずかしい
A drug is ordered at 5 micrograms/kg/min for an 80 kg patient. The infusion contains 1,600 micrograms per mL. What rate in mL/h is needed?
- A4 mL/h
- B15 mL/h
- C150 mL/h
- D25 mL/h
解答
- 1. C · To reduce confusion between look-alike drug names
- 2. C · Cyclo-oxygenase-2 (COX-2)
- 3. C · To speed up fetal lung maturity
- 4. D · It greatly raises the risk of Stevens–Johnson syndrome
- 5. A · 半減期の 4~5 倍
- 6. B · 低血糖
- 7. C · "I will stop eating all green vegetables from now on."
- 8. B · 15 mL/h
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