1.やさしい
Drugs whose names end in "-pril", such as lisinopril, belong to which class?
- ACalcium channel blockers
- BBeta blockers
- CAngiotensin II receptor blockers
- DACE inhibitors
2.やさしい
What does "bacteriostatic" mean?
- AThe drug kills viruses as well as bacteria
- BThe drug stops bacteria multiplying without killing them directly
- CThe drug kills bacteria directly by breaking down their cell wall
- DThe drug prevents the patient's immune response
3.やさしい
Why is vitamin K given to newborn babies?
- ATo prevent neonatal jaundice in the first week
- BTo prevent vitamin K deficiency bleeding
- CTo protect against hepatitis B
- DTo improve weight gain
4.ふつう
A malnourished patient with alcohol dependence needs IV glucose. Which vitamin should be given before or with it?
- AThiamine (vitamin B1)
- BVitamin K (phytomenadione)
- CVitamin C
- DVitamin D
5.ふつう
Why is ketorolac given only for a short course?
- AIt causes respiratory depression after a few days
- BGI bleeding and kidney injury become more likely with longer use
- CIt quickly loses all its pain-relieving effect because of tolerance
- DIt is a strong opioid that causes addiction
6.ふつう
ヘパリンはどのようにして抗凝固作用を生みますか?
- Aアンチトロンビンを増強し、トロンビンと第 Xa 因子を不活化させる
- B血小板の COX-1 を不可逆的に阻害する
- Cすでにある血栓のフィブリンを分解する
- D肝臓でのビタミン K 依存性凝固因子の合成を遮断する
7.むずかしい
A patient taking long-term hydroxychloroquine for lupus is advised to have regular eye examinations. Why?
- AThe drug causes cataracts within a few weeks of starting
- BThe drug stains the cornea blue
- CThe drug raises pressure inside the eye
- DThe drug can cause retinal toxicity that may be permanent
8.むずかしい
A patient receiving frequent salbutamol (albuterol) nebulisers develops a fine tremor and a heart rate of 120 per minute. What is the best explanation?
- AThe patient is allergic to salbutamol and needs adrenaline
- BSalbutamol blocks muscarinic receptors in the heart
- CAt high doses it also stimulates beta receptors in skeletal muscle and the heart
- DSalbutamol causes high potassium, which speeds the heart and causes muscle twitching
解答
- 1. D · ACE inhibitors
- 2. B · The drug stops bacteria multiplying without killing them directly
- 3. B · To prevent vitamin K deficiency bleeding
- 4. A · Thiamine (vitamin B1)
- 5. B · GI bleeding and kidney injury become more likely with longer use
- 6. A · アンチトロンビンを増強し、トロンビンと第 Xa 因子を不活化させる
- 7. D · The drug can cause retinal toxicity that may be permanent
- 8. C · At high doses it also stimulates beta receptors in skeletal muscle and the heart
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