解答つき薬理学ワークシート

無料で印刷できる薬理学のワークシート：やさしい問題から試験レベルまで 8 問、解答つき。印刷するか PDF で保存できます。

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名前: ____________________   日付: ____________

1.やさしい

Venlafaxine belongs to which class of antidepressants?

  1. AMonoamine oxidase inhibitors
  2. BSerotonin–noradrenaline reuptake inhibitors (SNRIs)
  3. CTricyclic antidepressants
  4. DSelective serotonin reuptake inhibitors (SSRIs)
2.やさしい

In Addison's disease, fludrocortisone is given to replace which hormone?

  1. AThyroxine
  2. BAldosterone
  3. CAdrenaline
  4. DCortisol
3.やさしい

Why is adrenaline (epinephrine) sometimes added to a local anaesthetic injection?

  1. AIt makes the anaesthetic act on the brain as well
  2. BIt speeds up the removal of the anaesthetic from the tissue into the blood
  3. CIt prevents allergic reactions to the anaesthetic
  4. DIt constricts vessels, so the block lasts longer and less enters the blood
4.ふつう

部分作動薬を高用量の完全作動薬と一緒に投与します。反応はどうなりますか？

  1. A部分作動薬が受容体を奪い合うため、低下する
  2. B高用量の完全作動薬だけのときとまったく同じままである
  3. C両方の薬が受容体を活性化するため、2 倍になる
  4. D完全作動薬の最大値を超えて上昇する
5.ふつう

A patient with Addison's disease on hydrocortisone develops a fever with flu. What is the usual advice?

  1. AMake no change, as illness does not affect cortisol needs
  2. BHalve the hydrocortisone to reduce side effects
  3. CStop the hydrocortisone until the fever settles, to let the body recover
  4. DIncrease the dose as instructed (sick-day rules) and seek help if vomiting
6.ふつう

A patient takes theophylline for COPD. Which advice is most important?

  1. ATake extra doses when short of breath
  2. BDrink plenty of grapefruit juice each morning to improve absorption
  3. CAvoid potassium-rich foods such as bananas
  4. DLimit coffee, tea and cola, because caffeine adds to the side effects
7.むずかしい

A patient on long-term lithium passes large amounts of dilute urine and is always thirsty. What is the most likely explanation?

  1. AThe patient is drinking too much and lithium is unrelated
  2. BLithium causes type 1 diabetes by destroying the pancreatic beta cells
  3. CLithium blocks the kidney's response to ADH (nephrogenic diabetes insipidus)
  4. DLithium increases ADH release from the pituitary
8.むずかしい

A patient is switched from oral to intravenous morphine. Why is the IV dose lower than the oral dose?

  1. AIV morphine is excreted much more slowly by the kidney than oral morphine
  2. BThe oral route causes tolerance faster than the IV route
  3. CIV morphine is a stronger chemical form of the drug
  4. DOral morphine has a large first-pass effect, so less reaches the blood

解答

  1. 1. B · Serotonin–noradrenaline reuptake inhibitors (SNRIs)
  2. 2. B · Aldosterone
  3. 3. D · It constricts vessels, so the block lasts longer and less enters the blood
  4. 4. A · 部分作動薬が受容体を奪い合うため、低下する
  5. 5. D · Increase the dose as instructed (sick-day rules) and seek help if vomiting
  6. 6. D · Limit coffee, tea and cola, because caffeine adds to the side effects
  7. 7. C · Lithium blocks the kidney's response to ADH (nephrogenic diabetes insipidus)
  8. 8. D · Oral morphine has a large first-pass effect, so less reaches the blood

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