1.やさしい
How do second-generation antihistamines such as cetirizine and loratadine differ from older ones?
- AThey cause much less drowsiness
- BThey block H2 receptors in the stomach
- CThey are given only by injection
- DThey work only on the skin
2.やさしい
How long does it usually take for an SSRI to improve mood noticeably?
- ASeveral weeks
- BA few hours
- CAbout six months
- DOne or two days
3.やさしい
アトロピンはどの種類の受容体を遮断しますか?
- Aヒスタミン H1 受容体
- Bムスカリン性アセチルコリン受容体
- C神経筋接合部のニコチン性受容体
- Dβ1 アドレナリン受容体
4.ふつう
Why is propranolol usually avoided in patients with asthma?
- AIt stimulates alpha-1 receptors in the airways and raises blood pressure
- BIt causes tolerance to inhaled corticosteroids
- CIt increases mucus production by blocking histamine
- DIt blocks beta-2 receptors in the airways and can cause bronchospasm
5.ふつう
Which blood test is commonly used to monitor a continuous infusion of unfractionated heparin?
- AINR (international normalised ratio, prothrombin time)
- BHaemoglobin A1c
- CActivated partial thromboplastin time (aPTT)
- DSerum potassium
6.ふつう
A malnourished patient with alcohol dependence needs IV glucose. Which vitamin should be given before or with it?
- AThiamine (vitamin B1)
- BVitamin C
- CVitamin K (phytomenadione)
- DVitamin D
7.むずかしい
ACE 阻害薬と併用すると、命に関わる高カリウム血症を起こしうる薬のグループは?
- Aスピロノラクトンなどのカリウム保持性利尿薬
- Bチアジド系利尿薬
- Cプロトンポンプ阻害薬
- D高用量の静注フロセミドなどのループ利尿薬
8.むずかしい
ある薬の半減期は 6 時間です。血漿濃度は 80 mg/L です。一次速度の消失で追加投与がないとすると、18 時間後の濃度はいくつですか?
- A40 mg/L
- B26.7 mg/L
- C10 mg/L
- D20 mg/L
解答
- 1. A · They cause much less drowsiness
- 2. A · Several weeks
- 3. B · ムスカリン性アセチルコリン受容体
- 4. D · It blocks beta-2 receptors in the airways and can cause bronchospasm
- 5. C · Activated partial thromboplastin time (aPTT)
- 6. A · Thiamine (vitamin B1)
- 7. A · スピロノラクトンなどのカリウム保持性利尿薬
- 8. C · 10 mg/L
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