解答つき薬理学ワークシート

Which drug is the antidote for magnesium sulfate toxicity?

1. ANaloxone
2. BPotassium chloride
3. CProtamine sulfate
4. DCalcium gluconate

Why is magnesium sulfate given to a woman with severe pre-eclampsia?

1. ATo raise her blood pressure
2. BTo treat a urinary infection
3. CTo start labour contractions
4. DTo prevent eclamptic seizures

In Addison's disease, fludrocortisone is given to replace which hormone?

1. AAldosterone
2. BAdrenaline
3. CCortisol
4. DThyroxine

Methylergometrine (methylergonovine) is prescribed for postpartum bleeding. Which finding would make the nurse withhold it and check with the prescriber?

1. AHeart rate of 88 per minute
2. BHaemoglobin slightly below normal
3. CBlood pressure of 160/105 mmHg
4. DTemperature of 37.2 °C (99 °F)

Why is testing for HLA-B*15:02 recommended before carbamazepine in people of some Asian ancestries?

1. AThis gene variant makes carbamazepine ineffective
2. BIt greatly raises the risk of Stevens–Johnson syndrome
3. CThis gene variant causes carbamazepine to raise blood glucose
4. DThis gene variant speeds up the kidney excretion of carbamazepine

A prescriber gives a verbal medication order in an emergency. What should the nurse do?

1. AWrite it down and read it back to the prescriber to confirm
2. BAsk another nurse to remember the order
3. CRemember it and write it in the chart at the end of the shift
4. DGive the drug without recording the order

A patient on long-term lithium passes large amounts of dilute urine and is always thirsty. What is the most likely explanation?

1. ALithium causes type 1 diabetes by destroying the pancreatic beta cells
2. BThe patient is drinking too much and lithium is unrelated
3. CLithium increases ADH release from the pituitary
4. DLithium blocks the kidney's response to ADH (nephrogenic diabetes insipidus)

A drug is ordered at 5 micrograms/kg/min for an 80 kg patient. The infusion contains 1,600 micrograms per mL. What rate in mL/h is needed?

1. A25 mL/h
2. B15 mL/h
3. C4 mL/h
4. D150 mL/h