解答つき薬理学ワークシート

How does ezetimibe lower cholesterol?

1. AIt binds bile acids in the gut
2. BIt increases the excretion of cholesterol in the urine and bile
3. CIt inhibits HMG-CoA reductase in the liver
4. DIt reduces the absorption of cholesterol from the intestine

ペニシリン系は何を妨げて細菌を殺しますか？

1. ADNA の複製
2. Bリボソームでのタンパク質合成
3. C細胞壁の合成
4. D葉酸の合成

How does tamsulosin improve urine flow in benign prostatic hyperplasia?

1. AIt blocks alpha-1 receptors and relaxes prostate smooth muscle
2. BIt increases urine production in the kidney
3. CIt contracts the bladder muscle
4. DIt shrinks the prostate gland over months by blocking testosterone

Which blood test is used to monitor warfarin therapy?

1. APlatelet count
2. BINR (prothrombin time)
3. CSerum albumin
4. DActivated partial thromboplastin time (aPTT)

A patient has oral mucositis after chemotherapy. Which advice is appropriate?

1. ABrush hard with a firm toothbrush to remove debris
2. BEat spicy and acidic foods to stimulate healing
3. CUse a soft toothbrush and rinse with saline or a bland mouthwash
4. DUse an alcohol-based mouthwash several times a day to kill germs

A malnourished patient with alcohol dependence needs IV glucose. Which vitamin should be given before or with it?

1. AVitamin D
2. BVitamin C
3. CThiamine (vitamin B1)
4. DVitamin K (phytomenadione)

プロベネシドは血漿ペニシリン濃度を上げるために使われてきました。どのようにしてそうするのですか？

1. A腎臓でのペニシリンの尿細管分泌を遮断する
2. Bペニシリンを血漿タンパク質から追い出す
3. C小腸からのペニシリンの吸収を増やす
4. D肝臓でのペニシリンの代謝を阻害する

A patient with Parkinson's disease has nausea. Why should metoclopramide be avoided?

1. AIt blocks dopamine receptors in the brain and can worsen the parkinsonism
2. BIt causes severe diarrhoea in Parkinson's disease
3. CIt increases dopamine levels in the brain too much and causes psychosis
4. DIt inhibits the absorption of all oral drugs