1.やさしい
アテノロールのように名前が「-olol(-ロール)」で終わる薬は、どのクラスに属しますか?
- Aカルシウム拮抗薬
- Bβ遮断薬
- Cスタチン
- DACE 阻害薬
2.やさしい
Which intramuscular site is generally preferred for adults because it is far from major nerves and vessels?
- ADorsogluteal
- BDeltoid for large volumes
- CForearm
- DVentrogluteal
3.やさしい
Which adverse effect of ethambutol requires vision checks?
- APermanent dilation of the pupils
- BBleeding in the back of the eye
- CCataracts that form within a few days of starting
- DOptic neuritis, with blurred vision and colour blindness
4.ふつう
After instilling eye drops, why should the patient press gently on the inner corner of the eye for a minute or two?
- ATo reduce drainage into the nose and absorption into blood
- BTo stop the eye from producing tears for about an hour
- CTo spread the drop evenly over the eyelid
- DTo make the pupil dilate faster
5.ふつう
Which group of signs suggests opioid withdrawal?
- AConstipation, itching and a slow heart rate
- BPinpoint pupils, slow breathing and drowsiness
- CDry mouth, urinary retention, blurred vision and confusion
- DYawning, runny nose, sweating, dilated pupils and diarrhoea
6.ふつう
ニトログリセリン(GTN)はどのように狭心症を和らげますか?
- Aβ1 受容体を遮断して心拍を遅くする
- B冠動脈の血栓を溶かす
- C収縮力を高めて、心臓がより効率よく血液を送り出せるようにする
- D一酸化窒素を放出し、主に静脈を拡張して心臓の仕事量を減らす
7.むずかしい
薬 X は最大反応 100%、EC50 1 mg です。薬 Y は最大反応 100%、EC50 10 mg です。正しい記述はどれですか?
- AY は X より力価が高く、両者の有効性は同じである
- BX は Y より力価が高く、両者の有効性は同じである
- CX は Y より有効性が高い
- DY は X より有効性が高い
8.むずかしい
A patient with asthma starts timolol eye drops for glaucoma and soon becomes wheezy. What is the most likely explanation?
- ATimolol activates histamine receptors in the lungs
- BThe eye drops contain an allergen that causes hay fever and asthma
- CTimolol is absorbed and blocks beta-2 receptors in the airways
- DThe wheeze is unrelated to the eye drops
解答
- 1. B · β遮断薬
- 2. D · Ventrogluteal
- 3. D · Optic neuritis, with blurred vision and colour blindness
- 4. A · To reduce drainage into the nose and absorption into blood
- 5. D · Yawning, runny nose, sweating, dilated pupils and diarrhoea
- 6. D · 一酸化窒素を放出し、主に静脈を拡張して心臓の仕事量を減らす
- 7. B · X は Y より力価が高く、両者の有効性は同じである
- 8. C · Timolol is absorbed and blocks beta-2 receptors in the airways
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