解答つき薬理学ワークシート

In Addison's disease, fludrocortisone is given to replace which hormone?

1. AAdrenaline
2. BThyroxine
3. CCortisol
4. DAldosterone

What is the most common side effect of first-generation antihistamines such as diphenhydramine?

1. ARaised blood pressure
2. BInsomnia
3. CDiarrhoea
4. DDrowsiness

薬物代謝の典型的な第 II 相（抱合）反応はどれですか？

1. A加水分解
2. B還元
3. Cグルクロン酸抱合
4. D酸化

Which adverse effect of ciprofloxacin should a patient report at once?

1. AA slightly bitter or metallic taste for a while after each dose
2. BMild tiredness in the first few days
3. CDarker stools than usual
4. DPain or swelling in a tendon, such as the Achilles tendon

Which adverse effect is a well-known risk of zidovudine?

1. ABone marrow suppression, especially anaemia
2. BGum overgrowth
3. CRed–green colour blindness
4. DOrange-red colouring of the urine and tears

Why should NSAIDs be used with caution in some people with asthma?

1. AThey cause mucus plugs by drying the airways
2. BThey can trigger bronchospasm in aspirin-sensitive asthma
3. CThey increase the clearance of salbutamol
4. DThey block the anti-inflammatory effect of inhaled corticosteroids

プロベネシドは血漿ペニシリン濃度を上げるために使われてきました。どのようにしてそうするのですか？

1. Aペニシリンを血漿タンパク質から追い出す
2. B小腸からのペニシリンの吸収を増やす
3. C腎臓でのペニシリンの尿細管分泌を遮断する
4. D肝臓でのペニシリンの代謝を阻害する

An older patient who has taken omeprazole for many years has muscle cramps, tremor and an irregular heartbeat. Which lab finding is most likely linked to the drug?

1. ALow serum glucose
2. BLow serum magnesium
3. CHigh serum calcium
4. DHigh serum sodium