解答つき薬理学ワークシート

Venlafaxine belongs to which class of antidepressants?

1. ASelective serotonin reuptake inhibitors (SSRIs)
2. BMonoamine oxidase inhibitors
3. CSerotonin–noradrenaline reuptake inhibitors (SNRIs)
4. DTricyclic antidepressants

Which intramuscular site is generally preferred for adults because it is far from major nerves and vessels?

1. AVentrogluteal
2. BDeltoid for large volumes
3. CDorsogluteal
4. DForearm

Chlordiazepoxide is commonly used to manage:

1. AMigraine prevention
2. BOpioid overdose
3. CBipolar mania
4. DAlcohol withdrawal

After instilling eye drops, why should the patient press gently on the inner corner of the eye for a minute or two?

1. ATo reduce drainage into the nose and absorption into blood
2. BTo stop the eye from producing tears for about an hour
3. CTo spread the drop evenly over the eyelid
4. DTo make the pupil dilate faster

薬のクリアランスは何を表しますか？

1. A単位時間あたりに薬が除去される血漿の容積
2. B1 回の透析で除去される薬の量
3. C投与量のうち吸収される割合
4. D薬が血漿から完全に消えるまでに必要な時間

A patient with Addison's disease on hydrocortisone develops a fever with flu. What is the usual advice?

1. AIncrease the dose as instructed (sick-day rules) and seek help if vomiting
2. BMake no change, as illness does not affect cortisol needs
3. CStop the hydrocortisone until the fever settles, to let the body recover
4. DHalve the hydrocortisone to reduce side effects

一次消失の薬で、投与間隔を変えずに投与量を 2 倍にすると：

1. A定常状態の濃度は 2 倍になるが、到達までの時間は変わらない
2. B定常状態に達する時間が半分になる
3. C定常状態の濃度は変わらないが、到達までの時間が半分になる
4. D半減期が 2 倍になる

How does levonorgestrel emergency contraception mainly work?

1. AIt kills sperm in the vagina
2. BIt causes an immediate period
3. CIt delays or prevents ovulation
4. DIt ends an established pregnancy