1.やさしい
Epoetin alfa, often used in chronic kidney disease, stimulates the production of:
- AClotting factors
- BRed blood cells
- CWhite blood cells
- DPlatelets
2.やさしい
Stimulation of which receptor increases heart rate and the force of contraction?
- ABeta-2 adrenergic receptor
- BAlpha-2 adrenergic receptor
- CBeta-1 adrenergic receptor
- DMuscarinic M2 receptor
3.やさしい
Amphotericin B is used mainly for:
- AMild athlete's foot
- BBacterial urinary tract infections
- CInfluenza in older people
- DSerious systemic fungal infections
4.ふつう
イブプロフェンなどの NSAIDs が胃潰瘍のリスクを高めるのはなぜですか?
- A胃酸の pH を上げるから
- B胃の中のヘリコバクター・ピロリの数を増やすから
- C胃粘膜を守るプロスタグランジンを減らすから
- D粘液層を直接溶かすから
5.ふつう
Why is testing for HLA-B*15:02 recommended before carbamazepine in people of some Asian ancestries?
- AThis gene variant speeds up the kidney excretion of carbamazepine
- BIt greatly raises the risk of Stevens–Johnson syndrome
- CThis gene variant causes carbamazepine to raise blood glucose
- DThis gene variant makes carbamazepine ineffective
6.ふつう
During an oxytocin infusion, contractions become very frequent and the fetal heart rate shows late decelerations. What is the nurse's first action?
- APosition the woman flat on her back
- BIncrease the infusion to finish labour quickly
- CStop the oxytocin infusion
- DGive a second oxytocin bolus
7.むずかしい
A patient on rifampicin, isoniazid, pyrazinamide and ethambutol develops a painful swollen big toe. Which drug is most likely responsible?
- AIsoniazid
- BPyrazinamide
- CEthambutol
- DRifampicin
8.むずかしい
β 遮断薬が糖尿病の人で低血糖の警告症状を隠すことがあるのはなぜですか?
- Aふるえや動悸などのアドレナリン作動性症状を弱めるから
- Bインスリン分泌を完全に止めるから
- C発熱を起こして発汗を隠すから
- D血糖を上げるので、低血糖がまったく起こらなくなるから
解答
- 1. B · Red blood cells
- 2. C · Beta-1 adrenergic receptor
- 3. D · Serious systemic fungal infections
- 4. C · 胃粘膜を守るプロスタグランジンを減らすから
- 5. B · It greatly raises the risk of Stevens–Johnson syndrome
- 6. C · Stop the oxytocin infusion
- 7. B · Pyrazinamide
- 8. A · ふるえや動悸などのアドレナリン作動性症状を弱めるから
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