解答つき薬理学ワークシート

Which drug is the antidote for paracetamol (acetaminophen) overdose?

1. AAcetylcysteine
2. BNaloxone
3. CVitamin K
4. DFlumazenil

Desmopressin is a synthetic analogue of which hormone?

1. AOxytocin, the hormone of labour
2. BAntidiuretic hormone (vasopressin)
3. CInsulin
4. DAldosterone

薬物代謝の典型的な第 II 相（抱合）反応はどれですか？

1. Aグルクロン酸抱合
2. B還元
3. C加水分解
4. D酸化

薬のクリアランスは何を表しますか？

1. A単位時間あたりに薬が除去される血漿の容積
2. B1 回の透析で除去される薬の量
3. C薬が血漿から完全に消えるまでに必要な時間
4. D投与量のうち吸収される割合

Why should loperamide usually be avoided in bloody diarrhoea with fever?

1. ALoperamide causes severe hypertension when there is an infection
2. BLoperamide is an antibiotic that causes resistance
3. CLoperamide makes the bleeding worse by blocking platelets
4. DSlowing the gut may keep bacteria and toxins in the bowel longer

100 mL of an antibiotic is to be given over 30 minutes using a giving set of 20 drops/mL. What is the drip rate?

1. AAbout 67 drops per minute
2. BAbout 20 drops per minute
3. CAbout 100 drops per minute
4. DAbout 33 drops per minute

腎不全のためにある薬のクリアランスが半分に下がり、分布容積は変わりません。半減期はどうなりますか？

1. A変わらない
2. B半分になる
3. C4 倍になる
4. D2 倍になる

A postoperative patient using morphine PCA is very drowsy, hard to rouse and has a respiratory rate of 7 per minute. What should the nurse do first?

1. AReduce the PCA dose and leave the pump running
2. BStop the PCA, try to rouse the patient and give naloxone as per protocol
3. CLet the patient sleep and recheck in one hour
4. DEncourage the patient to press the button only when awake and in pain