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Vardas: ____________________ Data: ____________
1.Lengvas
Buspirone is used mainly to treat:
APanic attacks needing immediate relief
BAcute alcohol withdrawal
CSevere pain
DGeneralised anxiety disorder
2.Lengvas
Ką apibūdina vaisto „stiprumas“ (potency)?
AKiek laiko vaistas išlieka organizme
BKiek vaistas saugus, palyginti su kitais tos pačios klasės vaistais
CDidžiausią poveikį, kurį vaistas gali sukelti
DVaisto kiekį, reikalingą tam tikram poveikiui sukelti
3.Lengvas
What is enzyme induction?
AA drug blocks liver enzymes, so other drugs build up in the blood
BA drug is converted into an enzyme in the body
CA drug speeds up liver enzymes, so other drugs are broken down faster
DA drug causes an allergic reaction to enzymes
4.Vidutinis
Kuris yra gerai žinomas ilgalaikio geriamųjų kortikosteroidų vartojimo nepageidaujamas poveikis?
AŽemas kraujospūdis
BOsteoporozė
CHipoglikemija
DSvorio mažėjimas
5.Vidutinis
Which assessments are most important during a magnesium sulfate infusion?
ABlood glucose, pupil size and pupil reaction to light
BDeep tendon reflexes, respiratory rate and urine output
CBowel sounds and appetite
DTemperature and skin colour only
6.Vidutinis
Why are patients taking simvastatin often advised to avoid large amounts of grapefruit juice?
AGrapefruit speeds up simvastatin breakdown in the liver, so the drug stops working
BGrapefruit makes the tablet dissolve in the mouth
CGrapefruit blocks cholesterol absorption and causes low cholesterol
DGrapefruit inhibits CYP3A4 in the gut, raising simvastatin levels and myopathy risk
7.Sunkus
A baby born to a mother on methadone becomes irritable on day 2, with a high-pitched cry, tremors, sneezing and poor feeding. What is the most likely cause?
ANeonatal hypoglycaemia from maternal diabetes
BNormal newborn behaviour
CNeonatal opioid withdrawal syndrome
DVitamin K deficiency bleeding
8.Sunkus
A patient taking long-term morphine for cancer pain becomes very sedated with slow breathing. Why is naloxone given in small, diluted doses?
ABecause naloxone is much more potent and toxic in patients with cancer
BBecause naloxone is toxic to the liver in large doses
CTo restore breathing without causing severe withdrawal and pain
DTo make the effect of naloxone last longer than morphine
Atsakymai
1. D · Generalised anxiety disorder
2. D · Vaisto kiekį, reikalingą tam tikram poveikiui sukelti
3. C · A drug speeds up liver enzymes, so other drugs are broken down faster
4. B · Osteoporozė
5. B · Deep tendon reflexes, respiratory rate and urine output
6. D · Grapefruit inhibits CYP3A4 in the gut, raising simvastatin levels and myopathy risk
7. C · Neonatal opioid withdrawal syndrome
8. C · To restore breathing without causing severe withdrawal and pain
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