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Vardas: ____________________ Data: ____________
1.Lengvas
Why is carbidopa combined with levodopa?
AIt stops levodopa turning into dopamine outside the brain
BIt converts levodopa into dopamine inside the gut
CIt increases the breakdown of dopamine in the liver
DIt blocks dopamine receptors to reduce nausea in the brain
2.Lengvas
Kas yra terapinis indeksas?
ALaikas iki pusiausvyros būsenos
BDozių skaičius per parą
CGeriamos dozės dalis, patenkanti į sisteminę kraujotaką, išreikšta procentais
DToksinės ir veiksmingos dozės santykis
3.Lengvas
Drugs whose names end in "-sartan", such as losartan, belong to which class?
ALoop diuretics
BACE inhibitors, which block the converting enzyme
CAngiotensin II receptor blockers
DAlpha-1 blockers
4.Vidutinis
A patient is starting olanzapine. Which monitoring is most important over the following months?
AHearing tests and vision tests every month
BPeak expiratory flow
CWeight, blood glucose and blood lipids
DINR and platelet count
5.Vidutinis
When should a patient take a once-daily proton pump inhibitor such as omeprazole?
AOnly when heartburn is severe
BAbout 30–60 minutes before the first meal of the day
CStraight after a large evening meal
DWith a glass of milk at bedtime, when acid output is highest
6.Vidutinis
A patient takes cholestyramine. How should other oral medicines be timed?
ATake them all at the same time as cholestyramine
BTake them 1 hour before or several hours after cholestyramine
CMix them into the cholestyramine drink so they are taken together
DTiming does not matter, as cholestyramine is not absorbed
7.Sunkus
A patient with diabetic ketoacidosis is about to start an IV insulin infusion. Serum potassium is 3,1 mmol/L (mEq/L). Why is this a concern?
AInsulin raises potassium further and can cause cardiac arrest, so the infusion is given faster
BInsulin moves potassium into cells, so the level can fall dangerously low
CPotassium has no link with insulin, so the infusion is started as planned
DLow potassium makes insulin ineffective, so a higher dose is needed
8.Sunkus
A patient taking digoxin has nausea, yellow-green vision and a dangerous arrhythmia. Which specific treatment can bind the drug?
AProtamine sulfate
BFlumazenil
CDigoxin immune Fab (antibody fragments)
DIntravenous vitamin K (phytomenadione) given slowly
Atsakymai
1. A · It stops levodopa turning into dopamine outside the brain
2. D · Toksinės ir veiksmingos dozės santykis
3. C · Angiotensin II receptor blockers
4. C · Weight, blood glucose and blood lipids
5. B · About 30–60 minutes before the first meal of the day
6. B · Take them 1 hour before or several hours after cholestyramine
7. B · Insulin moves potassium into cells, so the level can fall dangerously low
8. C · Digoxin immune Fab (antibody fragments)
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