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Nama: ____________________ Tarikh: ____________
1.Mudah
Manakah antara berikut ialah tindak balas fasa II (konjugasi) yang tipikal dalam metabolisme ubat?
AGlukuronidasi
BHidrolisis
CPengoksidaan
DPenurunan
2.Mudah
Which drug is the antidote for magnesium sulfate toxicity?
APotassium chloride
BProtamine sulfate
CCalcium gluconate
DNaloxone
3.Mudah
Disulfiram is used in alcohol use disorder because it:
ACures liver damage caused by alcohol
BCauses an unpleasant reaction if alcohol is drunk
CReplaces alcohol at its receptors in the brain
DRemoves alcohol from the blood faster
4.Sederhana
Apakah yang menjadikan terlebih dos antidepresan trisiklik seperti amitriptilin amat berbahaya?
AKegagalan hati teruk dalam beberapa jam
BGlukosa darah tinggi mendadak
CAritmia jantung dan sawan
DBatu karang
5.Sederhana
A patient starting niacin (nicotinic acid) complains of flushing and warmth after doses. Which advice may reduce this?
ATake aspirin 30 minutes before the niacin, if the prescriber agrees
BTake the niacin with a hot drink so that it dissolves and acts faster
CTake it on an empty stomach in a hot bath
DDouble the dose to build tolerance faster
6.Sederhana
A patient takes low-dose weekly methotrexate for rheumatoid arthritis. Which monitoring is needed?
ARegular blood count, liver and kidney function tests
BMonthly hearing tests
CDaily blood glucose checks
DWeekly INR checks and a monthly ECG to check the heart rhythm
7.Sukar
Why are oral liquid medicines drawn up in dedicated oral or enteral syringes that do not fit IV connectors?
ATo keep the medicine sterile for injection
BTo make the oral dose more accurate than a dose given through an IV syringe
CBecause IV syringes cannot hold liquids
DTo prevent oral liquids being given intravenously by mistake
8.Sukar
Two days after starting chemotherapy for a leukaemia with a high white cell count, a patient has reduced urine output. Which lab pattern suggests tumour lysis syndrome?
AHigh potassium, high phosphate, high uric acid and low calcium
BNormal electrolytes with a high haemoglobin
CHigh sodium, high glucose and low potassium
DLow potassium, low phosphate, low uric acid and high calcium
Kunci jawapan
1. A · Glukuronidasi
2. C · Calcium gluconate
3. B · Causes an unpleasant reaction if alcohol is drunk
4. C · Aritmia jantung dan sawan
5. A · Take aspirin 30 minutes before the niacin, if the prescriber agrees
6. A · Regular blood count, liver and kidney function tests
7. D · To prevent oral liquids being given intravenously by mistake
8. A · High potassium, high phosphate, high uric acid and low calcium
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