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Nama: ____________________ Tarikh: ____________
1.Mudah
How does ezetimibe lower cholesterol?
AIt reduces the absorption of cholesterol from the intestine
BIt binds bile acids in the gut
CIt inhibits HMG-CoA reductase in the liver
DIt increases the excretion of cholesterol in the urine and bile
2.Mudah
Why is HIV treated with a combination of antiretroviral drugs?
ATo suppress the virus and prevent drug resistance
BBecause one drug alone causes no side effects
CBecause each single drug cures only part of the infection
DTo make the treatment shorter, usually a few weeks
3.Mudah
In the United States, what does a Schedule II controlled substance mean?
AA drug with accepted medical use but a high risk of abuse
BA drug with almost no risk of abuse
CA drug available freely over the counter
DA drug with no accepted medical use and a high potential for abuse
4.Sederhana
After several years of levodopa treatment, which problem is common?
ADyskinesias and "on–off" fluctuations in response
BSevere hypoglycaemia after each dose
CPermanent hearing loss
DComplete and permanent loss of all Parkinson's symptoms
5.Sederhana
Besides lithium levels, which blood tests are monitored in long-term lithium treatment?
ATroponin and CK-MB
BLiver enzymes, serum amylase and lipase
CINR and fibrinogen
DKidney function and thyroid function
6.Sederhana
Mengapakah pesakit yang mengambil klozapin memerlukan kiraan darah berkala?
AIa mengubah kumpulan darah
BIa menaikkan kiraan platelet dengan berbahaya
CIa sering menyebabkan anemia kekurangan zat besi
DIa boleh menyebabkan agranulositosis
7.Sukar
A patient with asthma starts timolol eye drops for glaucoma and soon becomes wheezy. What is the most likely explanation?
AThe eye drops contain an allergen that causes hay fever and asthma
BTimolol activates histamine receptors in the lungs
CThe wheeze is unrelated to the eye drops
DTimolol is absorbed and blocks beta-2 receptors in the airways
8.Sukar
An older patient with coronary artery disease is starting levothyroxine for hypothyroidism. Why is a low starting dose used?
AFast replacement raises cardiac oxygen demand and can cause angina
BOlder patients absorb levothyroxine much better, so small doses are all they need
CHigh starting doses cause permanent hypothyroidism
DLevothyroxine causes severe hypoglycaemia in older patients
Kunci jawapan
1. A · It reduces the absorption of cholesterol from the intestine
2. A · To suppress the virus and prevent drug resistance
3. A · A drug with accepted medical use but a high risk of abuse
4. A · Dyskinesias and "on–off" fluctuations in response
5. D · Kidney function and thyroid function
6. D · Ia boleh menyebabkan agranulositosis
7. D · Timolol is absorbed and blocks beta-2 receptors in the airways
8. A · Fast replacement raises cardiac oxygen demand and can cause angina
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