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Nama: ____________________ Tarikh: ____________
1.Mudah
Apakah tindak balas ubat yang buruk (adverse drug reaction)?
ASebarang kesan ubat yang disedari pesakit
BTindak balas berbahaya yang tidak diingini terhadap ubat pada dos normal
CTindak balas yang berlaku hanya selepas terlebih dos
DKesan terapeutik yang dimaksudkan bagi sesuatu ubat
2.Mudah
Finasteride is used in benign prostatic hyperplasia because it:
AKills bacteria in the prostate
BRelaxes smooth muscle in the prostate within hours of the first dose
CIncreases testosterone production
DInhibits 5-alpha reductase and slowly shrinks the prostate
3.Mudah
Propofol is mainly used for:
ALong-term treatment of epilepsy at home by mouth
BInducing and maintaining anaesthesia, and ICU sedation
CTreating nausea after chemotherapy
DPain relief after surgery on the ward
4.Sederhana
A woman taking tamoxifen should report which symptom promptly?
AMild hot flushes, especially at night, in the first months
BUnusual vaginal bleeding or a painful swollen leg
CMild tiredness in the afternoon
DSlightly dry skin
5.Sederhana
A patient takes low-dose weekly methotrexate for rheumatoid arthritis. Which monitoring is needed?
ARegular blood count, liver and kidney function tests
BDaily blood glucose checks
CWeekly INR checks and a monthly ECG to check the heart rhythm
DMonthly hearing tests
6.Sederhana
A patient receives lactulose for hepatic encephalopathy. Which finding shows that it is working?
ATen watery stools a day and a low serum potassium
BBetter alertness and orientation, with two to three soft stools a day
CNo bowel movement for three days, with less confusion than before
DHigher blood ammonia with improved appetite
7.Sukar
Before starting rituximab, patients are tested for hepatitis B. Why?
ARituximab is a vaccine against hepatitis B
BHepatitis B infection makes rituximab completely ineffective
CRituximab can reactivate hepatitis B and cause liver failure
DRituximab is made from the hepatitis B virus
8.Sukar
A patient with myasthenia gravis took extra pyridostigmine doses. She now has increasing weakness, heavy salivation, sweating, small pupils and diarrhoea. What is the most likely cause?
AMyasthenic crisis from too little anticholinesterase drug
BCholinergic crisis from too much anticholinesterase drug
CAn allergic reaction to pyridostigmine
DA stroke unrelated to the medication
Kunci jawapan
1. B · Tindak balas berbahaya yang tidak diingini terhadap ubat pada dos normal
2. D · Inhibits 5-alpha reductase and slowly shrinks the prostate
3. B · Inducing and maintaining anaesthesia, and ICU sedation
4. B · Unusual vaginal bleeding or a painful swollen leg
5. A · Regular blood count, liver and kidney function tests
6. B · Better alertness and orientation, with two to three soft stools a day
7. C · Rituximab can reactivate hepatitis B and cause liver failure
8. B · Cholinergic crisis from too much anticholinesterase drug
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