Werkblad Farmacologie met antwoorden

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Naam: ____________________   Datum: ____________

1.Makkelijk

How do second-generation antihistamines such as cetirizine and loratadine differ from older ones?

  1. AThey work only on the skin
  2. BThey block H2 receptors in the stomach
  3. CThey are given only by injection
  4. DThey cause much less drowsiness
2.Makkelijk

How does allopurinol prevent gout?

  1. AIt increases the kidney excretion of calcium
  2. BIt dissolves crystals already in the joint within hours
  3. CIt inhibits xanthine oxidase, so less uric acid is made
  4. DIt blocks prostaglandins in the inflamed joint
3.Makkelijk

Which drug is an antidote for methanol or ethylene glycol (antifreeze) poisoning?

  1. ANaloxone
  2. BFomepizole
  3. CAtropine
  4. DFlumazenil
4.Gemiddeld

Why should a patient rinse the mouth after using an inhaled corticosteroid?

  1. ATo make the drug work faster in the lungs
  2. BTo reduce the risk of oral thrush (candidiasis) and hoarseness
  3. CTo stop the drug being absorbed too quickly into the blood
  4. DTo prevent a fall in blood glucose
5.Gemiddeld

Welke factor verhoogt het risico op lithiumintoxicatie?

  1. AUitdroging
  2. BDe dosis met voedsel innemen
  3. CEen zoutrijk dieet
  4. DExtra water drinken
6.Gemiddeld

Which approach is usually recommended to prevent constipation in a patient on regular opioids?

  1. AA stimulant laxative such as senna, often with a stool softener
  2. BBulk-forming fibre alone, with fluid intake restricted
  3. CAn antidiarrhoeal drug at night to slow the gut
  4. DNo laxative until the patient has not opened the bowels for a week
7.Moeilijk

A patient on methadone is also prescribed diazepam for anxiety. What is the main safety concern?

  1. AAdditive sedation and respiratory depression
  2. BSevere hypertension from the combination
  3. CMethadone causes diazepam to be excreted very quickly
  4. DDiazepam blocks the effect of methadone completely
8.Moeilijk

A drug is ordered at 5 micrograms/kg/min for an 80 kg patient. The infusion contains 1,600 micrograms per mL. What rate in mL/h is needed?

  1. A15 mL/h
  2. B25 mL/h
  3. C150 mL/h
  4. D4 mL/h

Antwoordenblad

  1. 1. D · They cause much less drowsiness
  2. 2. C · It inhibits xanthine oxidase, so less uric acid is made
  3. 3. B · Fomepizole
  4. 4. B · To reduce the risk of oral thrush (candidiasis) and hoarseness
  5. 5. A · Uitdroging
  6. 6. A · A stimulant laxative such as senna, often with a stool softener
  7. 7. A · Additive sedation and respiratory depression
  8. 8. A · 15 mL/h

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