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Naam: ____________________ Datum: ____________
1.Makkelijk
Welk plasma-eiwit bindt de meeste zure geneesmiddelen, zoals warfarine?
AHemoglobine
BFibrinogeen
CAlbumine
DInsuline
2.Makkelijk
How does allopurinol prevent gout?
AIt inhibits xanthine oxidase, so less uric acid is made
BIt dissolves crystals already in the joint within hours
CIt increases the kidney excretion of calcium
DIt blocks prostaglandins in the inflamed joint
3.Makkelijk
What is the purpose of the Z-track technique for intramuscular injections?
ATo make the injection faster
BTo stop the drug leaking back into the subcutaneous tissue
CTo avoid the need to clean the skin
DTo allow a larger volume to be given than with a standard injection
4.Gemiddeld
Hoe geeft heparine zijn antistollende effect?
AHet blokkeert in de lever de vitamine K-afhankelijke synthese van stollingsfactoren
BHet versterkt antitrombine, dat trombine en factor Xa inactiveert
CHet remt COX-1 in bloedplaatjes onomkeerbaar
DHet breekt fibrine in bestaande stolsels af
5.Gemiddeld
Bethanechol may be used for non-obstructive urinary retention. How does it work?
AIt increases urine production in the kidney
BIt blocks muscarinic receptors and relaxes the bladder wall muscle
CIt shrinks the prostate gland
DIt stimulates muscarinic receptors and contracts the bladder muscle
6.Gemiddeld
A patient with suspected sepsis has blood cultures ordered and a first antibiotic dose due. What should the nurse do?
AWait for the culture results before giving any antibiotic
BGive the antibiotic first, then take blood cultures the next day
CGive the antibiotic only if the temperature is above 40 °C (104 °F)
DTake the blood cultures first, then give the antibiotic at once
7.Moeilijk
A patient on digoxin is started on amiodarone. What change should the nurse expect?
ADigoxin levels fall sharply, so the digoxin dose is doubled
BNo interaction is expected
CDigoxin levels rise, so the digoxin dose is often reduced
DAmiodarone levels fall to zero
8.Moeilijk
Why is vancomycin given by mouth, not intravenously, for Clostridioides difficile infection?
AOral vancomycin is not absorbed, so it reaches high levels in the colon
BIntravenous vancomycin causes C. difficile infection
COral vancomycin is absorbed into the blood better than IV vancomycin
DThe oral form is cheaper but has the same effect as IV
Antwoordenblad
1. C · Albumine
2. A · It inhibits xanthine oxidase, so less uric acid is made
3. B · To stop the drug leaking back into the subcutaneous tissue
4. B · Het versterkt antitrombine, dat trombine en factor Xa inactiveert
5. D · It stimulates muscarinic receptors and contracts the bladder muscle
6. D · Take the blood cultures first, then give the antibiotic at once
7. C · Digoxin levels rise, so the digoxin dose is often reduced
8. A · Oral vancomycin is not absorbed, so it reaches high levels in the colon
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