Werkblad Farmacologie met antwoorden

Zolpidem is mainly prescribed for:

1. ALong-term treatment of depression
2. BTreatment of Parkinson's disease
3. CShort-term treatment of insomnia
4. DPrevention of migraine

Which opioid receptor is mainly responsible for the pain relief and respiratory depression of morphine?

1. AKappa receptor
2. BDelta receptor
3. CNicotinic receptor
4. DMu receptor

How does tramadol relieve pain?

1. AAntagonising NMDA receptors in the spinal cord and blocking sodium channels
2. BBlocking COX enzymes in the periphery
3. CWeak opioid agonism plus inhibiting the reuptake of serotonin and noradrenaline
4. DBlocking sodium channels in peripheral nerves

How should the nurse straighten the ear canal to give ear drops to a 2-year-old child?

1. APull the pinna up and back
2. BPull the pinna down and back
3. CPush the pinna forward and up
4. DLeave the ear untouched and drop into the canal

Which assessment is most important before giving a dose of IV morphine?

1. ABlood glucose and temperature, checked before each dose
2. BRespiratory rate and level of sedation
3. CPupil size and hearing
4. DBowel sounds and urine colour

During adult cardiac arrest, how often is IV adrenaline (epinephrine) usually repeated?

1. AEvery 3–5 minutes
2. BEvery 30 seconds
3. CEvery 15–20 minutes
4. DOnce only, at the start

Pasgeborenen die chlooramfenicol krijgen, kunnen het "grey baby syndrome" ontwikkelen. Wat is de belangrijkste reden?

1. APasgeborenen maken antistoffen tegen het middel
2. BEen onrijpe glucuronidering in de lever laat het middel stapelen
3. CDe nier van de pasgeborene scheidt het middel te snel uit, dus er worden hogere doses gegeven
4. DChlooramfenicol wordt bij neonaten omgezet in vitamine K

A patient taking dabigatran has a life-threatening bleed. Which specific reversal agent is used?

1. AAndexanet alfa
2. BIdarucizumab
3. CVitamin K
4. DProtamine sulfate