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Naam: ____________________ Datum: ____________
1.Makkelijk
Donepezil, used in Alzheimer's disease, belongs to which class?
AAcetylcholinesterase inhibitors
BDopamine agonists
CBenzodiazepines
DSelective serotonin reuptake inhibitors
2.Makkelijk
What is the purpose of the Z-track technique for intramuscular injections?
ATo allow a larger volume to be given than with a standard injection
BTo stop the drug leaking back into the subcutaneous tissue
CTo avoid the need to clean the skin
DTo make the injection faster
3.Makkelijk
What is drug synergism?
AOne drug cancels out the effect of another drug
BTwo drugs together produce exactly the sum of their separate effects
CTwo drugs together have a greater effect than the sum of each alone
DA drug loses its effect after repeated doses
4.Gemiddeld
Which approach is usually recommended to prevent constipation in a patient on regular opioids?
ANo laxative until the patient has not opened the bowels for a week
BBulk-forming fibre alone, with fluid intake restricted
CAn antidiarrhoeal drug at night to slow the gut
DA stimulant laxative such as senna, often with a stool softener
5.Gemiddeld
A man takes finasteride. What should be explained about handling the tablets?
APregnant women should not handle crushed or broken tablets
BAnyone can handle the tablets, as they contain no active drug
CThe tablets must be crushed before swallowing
DThe tablets must be stored in the fridge
6.Gemiddeld
A man taking tamsulosin is planning cataract surgery. What should the nurse advise?
ATell the eye surgeon, as it can cause floppy iris syndrome
BStop the drug for one day and no further action is needed
CTake a double dose on the day of surgery
DThe drug has no link with eye surgery
7.Moeilijk
Before starting rituximab, patients are tested for hepatitis B. Why?
AHepatitis B infection makes rituximab completely ineffective
BRituximab is a vaccine against hepatitis B
CRituximab can reactivate hepatitis B and cause liver failure
DRituximab is made from the hepatitis B virus
8.Moeilijk
A patient with epilepsy needs pain relief. Why is tramadol used with caution?
AIt lowers the seizure threshold
BIt always causes respiratory arrest in epilepsy
CIt causes a sharp rise in blood glucose
DIt speeds up the metabolism of all antiepileptic drugs
Antwoordenblad
1. A · Acetylcholinesterase inhibitors
2. B · To stop the drug leaking back into the subcutaneous tissue
3. C · Two drugs together have a greater effect than the sum of each alone
4. D · A stimulant laxative such as senna, often with a stool softener
5. A · Pregnant women should not handle crushed or broken tablets
6. A · Tell the eye surgeon, as it can cause floppy iris syndrome
7. C · Rituximab can reactivate hepatitis B and cause liver failure
8. A · It lowers the seizure threshold
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