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Naam: ____________________ Datum: ____________
1.Makkelijk
Infliximab and adalimumab are biological drugs that block:
AHistamine H1 receptors in the skin and airways
BTumour necrosis factor-alpha (TNF-alpha)
CInsulin receptors
DVitamin K recycling
2.Makkelijk
Why is adrenaline (epinephrine) sometimes added to a local anaesthetic injection?
AIt prevents allergic reactions to the anaesthetic
BIt constricts vessels, so the block lasts longer and less enters the blood
CIt speeds up the removal of the anaesthetic from the tissue into the blood
DIt makes the anaesthetic act on the brain as well
3.Makkelijk
Welk orgaan scheidt de meeste wateroplosbare geneesmiddelen en hun metabolieten uit?
ALong
BHuid
CLever
DNier
4.Gemiddeld
A patient takes cholestyramine. How should other oral medicines be timed?
AMix them into the cholestyramine drink so they are taken together
BTiming does not matter, as cholestyramine is not absorbed
CTake them 1 hour before or several hours after cholestyramine
DTake them all at the same time as cholestyramine
5.Gemiddeld
Why should loperamide usually be avoided in bloody diarrhoea with fever?
ALoperamide is an antibiotic that causes resistance
BLoperamide makes the bleeding worse by blocking platelets
CLoperamide causes severe hypertension when there is an infection
DSlowing the gut may keep bacteria and toxins in the bowel longer
6.Gemiddeld
A patient has oral mucositis after chemotherapy. Which advice is appropriate?
AUse a soft toothbrush and rinse with saline or a bland mouthwash
BEat spicy and acidic foods to stimulate healing
CBrush hard with a firm toothbrush to remove debris
DUse an alcohol-based mouthwash several times a day to kill germs
7.Moeilijk
Een middel heeft een halfwaardetijd van 6 uur. De plasmaspiegel is 80 mg/L. Wat is de spiegel na 18 uur, uitgaande van eerste-orde-eliminatie en geen verdere doses?
A10 mg/L
B26,7 mg/L
C20 mg/L
D40 mg/L
8.Moeilijk
Why is strict aseptic technique and a limited hang time needed for propofol infusions?
ALight exposure changes propofol into an opioid
BPropofol breaks down into a toxic gas after a few hours
CIts lipid emulsion lets bacteria grow if it is contaminated
DPropofol becomes more potent the longer it hangs
Antwoordenblad
1. B · Tumour necrosis factor-alpha (TNF-alpha)
2. B · It constricts vessels, so the block lasts longer and less enters the blood
3. D · Nier
4. C · Take them 1 hour before or several hours after cholestyramine
5. D · Slowing the gut may keep bacteria and toxins in the bowel longer
6. A · Use a soft toothbrush and rinse with saline or a bland mouthwash
7. A · 10 mg/L
8. C · Its lipid emulsion lets bacteria grow if it is contaminated
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