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Naam: ____________________ Datum: ____________
1.Makkelijk
Why is carbidopa combined with levodopa?
AIt converts levodopa into dopamine inside the gut
BIt stops levodopa turning into dopamine outside the brain
CIt blocks dopamine receptors to reduce nausea in the brain
DIt increases the breakdown of dopamine in the liver
2.Makkelijk
What is enzyme induction?
AA drug speeds up liver enzymes, so other drugs are broken down faster
BA drug is converted into an enzyme in the body
CA drug causes an allergic reaction to enzymes
DA drug blocks liver enzymes, so other drugs build up in the blood
3.Makkelijk
Disulfiram is used in alcohol use disorder because it:
ACauses an unpleasant reaction if alcohol is drunk
BCures liver damage caused by alcohol
CReplaces alcohol at its receptors in the brain
DRemoves alcohol from the blood faster
4.Gemiddeld
How should a patient take oral alendronate?
AWith milk at bedtime, then lying down straight away to aid absorption
BWith breakfast and coffee to protect the stomach
CCrushed into yoghurt with calcium supplements
DWith plain water on an empty stomach, staying upright for 30 minutes
5.Gemiddeld
A patient takes isoniazid. Which advice is most important?
AStop the drug when the cough improves
BAvoid alcohol and report jaundice, dark urine or poor appetite
CTake it with antacids to protect the stomach from irritation
DExpect the urine to turn orange
6.Gemiddeld
Aciclovir wordt vooral gebruikt voor infecties veroorzaakt door:
AHerpesvirussen zoals herpes simplex en varicellazoster
BInfluenza A-virus
CHiv
DBacteriën die bètalactamase maken
7.Moeilijk
Which finding most favours serotonin syndrome over neuroleptic malignant syndrome?
AA very high creatine kinase
BSlow onset over days with lead-pipe rigidity
CRapid onset with hyperreflexia and clonus
DRecent start of an antipsychotic drug
8.Moeilijk
A patient on disulfiram becomes flushed, nauseated and has palpitations after using a mouthwash. What is the most likely cause?
ADisulfiram toxicity from taking too many tablets by mistake
BAn allergy to mint flavouring in the mouthwash
CAlcohol in the mouthwash caused a disulfiram–alcohol reaction
DLow blood glucose from skipping breakfast
Antwoordenblad
1. B · It stops levodopa turning into dopamine outside the brain
2. A · A drug speeds up liver enzymes, so other drugs are broken down faster
3. A · Causes an unpleasant reaction if alcohol is drunk
4. D · With plain water on an empty stomach, staying upright for 30 minutes
5. B · Avoid alcohol and report jaundice, dark urine or poor appetite
6. A · Herpesvirussen zoals herpes simplex en varicellazoster
7. C · Rapid onset with hyperreflexia and clonus
8. C · Alcohol in the mouthwash caused a disulfiram–alcohol reaction
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