Werkblad Farmacologie met antwoorden

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Naam: ____________________   Datum: ____________

1.Makkelijk

How does rasagiline help in Parkinson's disease?

  1. AIt blocks acetylcholine receptors in the gut
  2. BIt is converted directly into dopamine inside brain neurones
  3. CIt inhibits MAO-B, so brain dopamine is broken down more slowly
  4. DIt blocks dopamine receptors in the brain
2.Makkelijk

How long does it usually take for an SSRI to improve mood noticeably?

  1. ASeveral weeks
  2. BAbout six months
  3. COne or two days
  4. DA few hours
3.Makkelijk

Infliximab and adalimumab are biological drugs that block:

  1. AInsulin receptors
  2. BVitamin K recycling
  3. CTumour necrosis factor-alpha (TNF-alpha)
  4. DHistamine H1 receptors in the skin and airways
4.Gemiddeld

A child is starting methylphenidate for ADHD. Which advice is appropriate?

  1. AExpect weight gain as the main side effect
  2. BGive the last dose at bedtime to help the child sleep
  3. CGive the drug only at weekends
  4. DGive doses early in the day and monitor appetite and growth
5.Gemiddeld

A 19-year-old starts an SSRI for depression. Which is most important for the nurse to monitor during the first weeks?

  1. ABlood glucose before every meal and at bedtime
  2. BNew or worsening suicidal thoughts or agitation
  3. CHearing loss and tinnitus
  4. DDaily bowel movements only
6.Gemiddeld

1000 mL of IV fluid is to be given over 8 hours with a pump. What rate should be set?

  1. A80 mL/h
  2. B100 mL/h
  3. C125 mL/h
  4. D250 mL/h
7.Moeilijk

A patient with heart failure starts taking naproxen regularly for back pain. Why is this a concern?

  1. ANSAIDs increase heart contractility too much
  2. BNSAIDs block the absorption of furosemide completely
  3. CNSAIDs lower potassium, which makes digoxin and diuretics fail
  4. DNSAIDs cause salt and water retention and can worsen heart failure
8.Moeilijk

A patient on long-term lithium passes large amounts of dilute urine and is always thirsty. What is the most likely explanation?

  1. ALithium increases ADH release from the pituitary
  2. BLithium blocks the kidney's response to ADH (nephrogenic diabetes insipidus)
  3. CLithium causes type 1 diabetes by destroying the pancreatic beta cells
  4. DThe patient is drinking too much and lithium is unrelated

Antwoordenblad

  1. 1. C · It inhibits MAO-B, so brain dopamine is broken down more slowly
  2. 2. A · Several weeks
  3. 3. C · Tumour necrosis factor-alpha (TNF-alpha)
  4. 4. D · Give doses early in the day and monitor appetite and growth
  5. 5. B · New or worsening suicidal thoughts or agitation
  6. 6. C · 125 mL/h
  7. 7. D · NSAIDs cause salt and water retention and can worsen heart failure
  8. 8. B · Lithium blocks the kidney's response to ADH (nephrogenic diabetes insipidus)

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