Werkblad Farmacologie met antwoorden

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Naam: ____________________   Datum: ____________

1.Makkelijk

Which adverse effect of ethambutol requires vision checks?

  1. AOptic neuritis, with blurred vision and colour blindness
  2. BBleeding in the back of the eye
  3. CPermanent dilation of the pupils
  4. DCataracts that form within a few days of starting
2.Makkelijk

Desmopressin is a synthetic analogue of which hormone?

  1. AOxytocin, the hormone of labour
  2. BAntidiuretic hormone (vasopressin)
  3. CAldosterone
  4. DInsulin
3.Makkelijk

Why is carbidopa combined with levodopa?

  1. AIt blocks dopamine receptors to reduce nausea in the brain
  2. BIt increases the breakdown of dopamine in the liver
  3. CIt converts levodopa into dopamine inside the gut
  4. DIt stops levodopa turning into dopamine outside the brain
4.Gemiddeld

How is adenosine given for supraventricular tachycardia?

  1. AAs a slow infusion over one hour
  2. BAs a rapid IV push followed by a fast saline flush
  3. CAs a tablet under the tongue
  4. DAs an intramuscular injection into the outer thigh muscle
5.Gemiddeld

Which adverse effect is a well-known risk of zidovudine?

  1. ARed–green colour blindness
  2. BOrange-red colouring of the urine and tears
  3. CGum overgrowth
  4. DBone marrow suppression, especially anaemia
6.Gemiddeld

Which antihypertensive class can raise blood glucose and uric acid levels, sometimes triggering gout?

  1. AThiazide diuretics
  2. BAngiotensin II receptor blockers
  3. CAlpha-1 blockers
  4. DACE inhibitors
7.Moeilijk

A patient with myasthenia gravis took extra pyridostigmine doses. She now has increasing weakness, heavy salivation, sweating, small pupils and diarrhoea. What is the most likely cause?

  1. ACholinergic crisis from too much anticholinesterase drug
  2. BA stroke unrelated to the medication
  3. CMyasthenic crisis from too little anticholinesterase drug
  4. DAn allergic reaction to pyridostigmine
8.Moeilijk

Why is the TPMT enzyme often tested before azathioprine is started?

  1. AHigh TPMT activity causes an allergic reaction to azathioprine
  2. BTPMT is needed to absorb azathioprine from the gut
  3. CTPMT testing shows whether the patient has tuberculosis
  4. DLow TPMT activity causes toxic levels and marrow suppression

Antwoordenblad

  1. 1. A · Optic neuritis, with blurred vision and colour blindness
  2. 2. B · Antidiuretic hormone (vasopressin)
  3. 3. D · It stops levodopa turning into dopamine outside the brain
  4. 4. B · As a rapid IV push followed by a fast saline flush
  5. 5. D · Bone marrow suppression, especially anaemia
  6. 6. A · Thiazide diuretics
  7. 7. A · Cholinergic crisis from too much anticholinesterase drug
  8. 8. D · Low TPMT activity causes toxic levels and marrow suppression

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