Werkblad Farmacologie met antwoorden

Which drug is the antidote for magnesium sulfate toxicity?

1. APotassium chloride
2. BNaloxone
3. CCalcium gluconate
4. DProtamine sulfate

Benzodiazepinen zoals diazepam werken door het effect van welke neurotransmitter te versterken?

1. ASerotonine
2. BNoradrenaline
3. CGABA
4. DGlutamaat

Disulfiram is used in alcohol use disorder because it:

1. ARemoves alcohol from the blood faster
2. BCauses an unpleasant reaction if alcohol is drunk
3. CCures liver damage caused by alcohol
4. DReplaces alcohol at its receptors in the brain

Which blood test is used to monitor warfarin therapy?

1. ASerum albumin
2. BActivated partial thromboplastin time (aPTT)
3. CPlatelet count
4. DINR (prothrombin time)

Which rule applies when giving phenytoin intravenously?

1. AMix it with glucose 5% to prevent low blood sugar
2. BMix or flush it only with normal saline and give it slowly
3. CGive it in the same line as other drugs without flushing
4. DGive it as a rapid push to stop seizures faster

Een middel remt het leverenzym CYP3A4. Wat kan er gebeuren met een tweede middel dat vooral via CYP3A4 wordt afgebroken?

1. ADe plasmaspiegel stijgt en de kans op bijwerkingen neemt toe
2. BNiets, want enzymen beïnvloeden andere middelen niet
3. CDe plasmaspiegel daalt en het kan bij de gebruikelijke dosis niet meer werken
4. DHet wordt sneller door de nieren uitgescheiden

A patient on disulfiram becomes flushed, nauseated and has palpitations after using a mouthwash. What is the most likely cause?

1. ADisulfiram toxicity from taking too many tablets by mistake
2. BLow blood glucose from skipping breakfast
3. CAn allergy to mint flavouring in the mouthwash
4. DAlcohol in the mouthwash caused a disulfiram–alcohol reaction

Lithium taken in the first trimester of pregnancy has been linked to which type of birth defect?

1. ACleft lip and palate only
2. BHeart malformations, such as Ebstein's anomaly
3. CLimb defects similar to thalidomide
4. DNeural tube defects such as spina bifida