Werkblad Farmacologie met antwoorden

Welk orgaan breekt de meeste geneesmiddelen af?

1. ALong
2. BNier
3. CMilt
4. DLever

Oseltamivir is used to treat or prevent which infection?

1. AHIV
2. BTuberculosis
3. CHerpes simplex
4. DInfluenza

Filgrastim, a granulocyte colony-stimulating factor (G-CSF), is given to:

1. AStop bleeding from wounds
2. BIncrease the production of platelets
3. CIncrease the production of neutrophils
4. DLower the white cell count in leukaemia

Which signs suggest early lithium toxicity?

1. ADiarrhoea, vomiting, coarse tremor and drowsiness
2. BPinpoint pupils and slow breathing
3. CVery high blood pressure and a severe headache
4. DHair loss and dark urine only

A patient receives lactulose for hepatic encephalopathy. Which finding shows that it is working?

1. ANo bowel movement for three days, with less confusion than before
2. BHigher blood ammonia with improved appetite
3. CBetter alertness and orientation, with two to three soft stools a day
4. DTen watery stools a day and a low serum potassium

A patient with a fentanyl patch is given home-care advice. Which instruction is correct?

1. AThrow used patches loose into the household bin with the packaging
2. BAvoid heating pads, hot baths and saunas over or near the patch
3. CApply each new patch over the same skin area
4. DCut the patch in half if the pain is mild

Het verdelingsvolume van een middel is erg groot (bijvoorbeeld 500 L bij een volwassene). Waar wijst dit op?

1. AHet middel blijft bijna volledig in het plasmacompartiment
2. BHet middel wordt snel door de nieren uitgescheiden
3. CHet middel wordt sterk door de weefsels opgenomen
4. DHet middel kan niet intraveneus worden gegeven

A man on long-term testosterone therapy has a rising haematocrit. Why is this important?

1. AA high haematocrit shows that the testosterone is not being absorbed
2. BIt means the testosterone dose is too low
3. CTestosterone raises red cell production, increasing clot risk
4. DIt is a sign of liver failure caused by testosterone