Werkblad Farmacologie met antwoorden

Which drug is first-line for symptomatic bradycardia in adults?

1. AMetoprolol
2. BAtropine
3. CDigoxin
4. DAdenosine

Een fentanylpleister op de huid is een voorbeeld van welke toedieningsweg?

1. AIntradermaal
2. BTransdermaal
3. CSubcutaan
4. DSublinguaal

What is enzyme induction?

1. AA drug causes an allergic reaction to enzymes
2. BA drug blocks liver enzymes, so other drugs build up in the blood
3. CA drug is converted into an enzyme in the body
4. DA drug speeds up liver enzymes, so other drugs are broken down faster

Wat beschrijft de klaring van een geneesmiddel?

1. AHet deel van de dosis dat wordt opgenomen
2. BDe hoeveelheid middel die in één dialysesessie wordt verwijderd
3. CDe tijd die nodig is om het middel volledig uit het plasma te laten verdwijnen
4. DHet volume plasma dat per tijdseenheid van het middel wordt gezuiverd

Why is directly observed therapy (DOT) often used for tuberculosis?

1. ATreatment lasts months, and missed doses cause resistance
2. BPatients with TB cannot swallow tablets
3. CTB drugs must always be given intravenously in hospital
4. DThe drugs work only if a nurse is present

Long-term use of metformin can cause a deficiency of which vitamin?

1. AVitamin K
2. BVitamin D
3. CVitamin A
4. DVitamin B12

Why is pethidine (meperidine) avoided in older people and in kidney impairment?

1. AIt has no pain-relieving effect in older people
2. BIt is not absorbed from the gut when kidney function is poor
3. CIt causes severe hypoglycaemia in these groups
4. DIts metabolite norpethidine builds up and can cause seizures

Which statement about raloxifene for postmenopausal osteoporosis is correct?

1. AIt acts like oestrogen in all tissues, including the breast, and relieves hot flushes
2. BIt has no effect on the risk of blood clots
3. CIt acts like oestrogen on bone but blocks oestrogen in the breast, and raises clot risk
4. DIt is a bisphosphonate taken weekly with water