Werkblad Farmacologie met antwoorden

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Naam: ____________________   Datum: ____________

1.Makkelijk

Penicillines doden bacteriën door te interfereren met:

  1. ADe foliumzuursynthese
  2. BDe celwandsynthese
  3. CDe eiwitsynthese op het ribosoom
  4. DDe DNA-replicatie
2.Makkelijk

Which vasopressor is usually first-line for septic shock that persists after fluids?

  1. ANoradrenaline (norepinephrine)
  2. BGlyceryl trinitrate
  3. CAdenosine
  4. DIsoprenaline (isoproterenol)
3.Makkelijk

Sumatriptan is used mainly to:

  1. ATreat high blood pressure
  2. BRelieve nerve pain from diabetes
  3. CPrevent epileptic seizures
  4. DTreat an acute migraine attack
4.Gemiddeld

Why should loperamide usually be avoided in bloody diarrhoea with fever?

  1. ALoperamide is an antibiotic that causes resistance
  2. BLoperamide causes severe hypertension when there is an infection
  3. CSlowing the gut may keep bacteria and toxins in the bowel longer
  4. DLoperamide makes the bleeding worse by blocking platelets
5.Gemiddeld

Which early signs suggest systemic toxicity from a local anaesthetic?

  1. ANumbness around the mouth, metallic taste and tinnitus
  2. BHeavy sweating, salivation and diarrhoea
  3. CItchy rash and swelling only at the injection site
  4. DPinpoint pupils and slow, shallow breathing
6.Gemiddeld

Which patient should usually not use the combined oral contraceptive pill?

  1. AA 30-year-old non-smoker with no medical problems
  2. BA 22-year-old non-smoker with acne
  3. CA 25-year-old woman with heavy periods
  4. DA 38-year-old woman who smokes 20 cigarettes a day
7.Moeilijk

A patient receiving a phenylephrine infusion has a rise in blood pressure and a fall in heart rate. What is the best explanation?

  1. AThe fall in heart rate shows phenylephrine toxicity of the AV node
  2. BPhenylephrine stimulates muscarinic receptors
  3. CPhenylephrine directly blocks beta-1 receptors in the heart's conduction system
  4. DAlpha-1 vasoconstriction raises blood pressure and causes reflex bradycardia
8.Moeilijk

A patient with heart failure on furosemide is also given metolazone, a thiazide-like diuretic. Which risk increases most?

  1. AHypoglycaemia and weight gain
  2. BSevere hypertension, tachycardia and fluid retention
  3. CSevere hypokalaemia, hyponatraemia and dehydration
  4. DHyperkalaemia and fluid overload

Antwoordenblad

  1. 1. B · De celwandsynthese
  2. 2. A · Noradrenaline (norepinephrine)
  3. 3. D · Treat an acute migraine attack
  4. 4. C · Slowing the gut may keep bacteria and toxins in the bowel longer
  5. 5. A · Numbness around the mouth, metallic taste and tinnitus
  6. 6. D · A 38-year-old woman who smokes 20 cigarettes a day
  7. 7. D · Alpha-1 vasoconstriction raises blood pressure and causes reflex bradycardia
  8. 8. C · Severe hypokalaemia, hyponatraemia and dehydration

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