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Naam: ____________________ Datum: ____________
1.Makkelijk
Wat betekent de "halfwaardetijd" van een geneesmiddel?
ADe tijd waarin de plasmaconcentratie halveert
BDe tijd tot het middel begint te werken
CDe helft van de tijd dat het middel in het lichaam blijft
DDe tijd tot de helft van de dosis uit de darm is opgenomen
2.Makkelijk
Welk orgaan scheidt de meeste wateroplosbare geneesmiddelen en hun metabolieten uit?
ALong
BNier
CLever
DHuid
3.Makkelijk
With patient-controlled analgesia (PCA), who should press the button to give a dose?
AThe nursing assistant at set times
BA family member when the patient is asleep
CAny visitor who thinks the patient is in pain
DOnly the patient
4.Gemiddeld
Why should loperamide usually be avoided in bloody diarrhoea with fever?
ASlowing the gut may keep bacteria and toxins in the bowel longer
BLoperamide makes the bleeding worse by blocking platelets
CLoperamide is an antibiotic that causes resistance
DLoperamide causes severe hypertension when there is an infection
5.Gemiddeld
During an amphotericin B infusion, the patient has fever, chills and shaking. What is the most likely explanation?
AA common infusion reaction to amphotericin B
BA sign that the drug has been given into an artery
CSevere hypoglycaemia caused by the drug
DA sign that the fungal infection is cured
6.Gemiddeld
A patient with suspected sepsis has blood cultures ordered and a first antibiotic dose due. What should the nurse do?
AWait for the culture results before giving any antibiotic
BTake the blood cultures first, then give the antibiotic at once
CGive the antibiotic first, then take blood cultures the next day
DGive the antibiotic only if the temperature is above 40 °C (104 °F)
7.Moeilijk
Before starting rituximab, patients are tested for hepatitis B. Why?
AHepatitis B infection makes rituximab completely ineffective
BRituximab can reactivate hepatitis B and cause liver failure
CRituximab is made from the hepatitis B virus
DRituximab is a vaccine against hepatitis B
8.Moeilijk
A patient on simvastatin is prescribed gemfibrozil. What is the main concern?
AA much higher risk of myopathy and rhabdomyolysis
BA sharp rise in LDL cholesterol and triglycerides
CLoss of all lipid-lowering effect
DSevere hypoglycaemia
Antwoordenblad
1. A · De tijd waarin de plasmaconcentratie halveert
2. B · Nier
3. D · Only the patient
4. A · Slowing the gut may keep bacteria and toxins in the bowel longer
5. A · A common infusion reaction to amphotericin B
6. B · Take the blood cultures first, then give the antibiotic at once
7. B · Rituximab can reactivate hepatitis B and cause liver failure
8. A · A much higher risk of myopathy and rhabdomyolysis
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