Human anatomy: practice questions with explanations

Free Human anatomy multiple-choice practice questions with hints and explanations, at three levels: key terms and facts, applying the concepts, cases and analysis.

Free practice problemEasy

Where are the alveoli found?

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What you practise

  1. Easykey terms and facts
  2. Mediumapplying the concepts
  3. Hardcases and analysis

Learn Human anatomy from scratch

1What anatomy is and why it matters

Anatomy is the study of the structure of the body: what the parts are called, where they lie and how they are connected. Physiology, a separate subject, studies how those parts work.

Doctors, nurses and therapists use anatomy every day. To give an injection, feel a pulse or understand an injury, you need to know exactly what lies under the skin at that spot.

The body is built in levels. Each level is made of the one below it:

  1. Cells, the smallest living units, such as muscle cells and nerve cells.
  2. Tissues, groups of similar cells doing one job. There are four basic types: epithelial, connective, muscle and nervous tissue.
  3. Organs, made of several tissues, such as the heart, the liver or the skin.
  4. Organ systems, groups of organs that work together, such as the cardiovascular, respiratory, digestive, nervous and musculoskeletal systems.

The skin is the largest organ of the body. The liver is the largest internal organ.

Self-check Which order goes from the smallest to the largest level of organisation?
  1. Cells, organs, tissues, organ systems
  2. Cells, tissues, organs, organ systems
  3. Organs, tissues, cells, organ systems
  4. Tissues, cells, organs, organ systems

Answer: Cells, tissues, organs, organ systems. Cells group into tissues, tissues build organs, and organs work together in systems. Putting organs before tissues is the usual slip: an organ such as the heart contains several tissues.

2The anatomical position and directions

Every direction in anatomy refers to one standard posture, the anatomical position: standing upright, facing forward, arms at the sides, palms facing forward and feet together.

Directions are always given from the patient’s point of view. “Left” means the patient’s left, even when the patient faces you.

The most important direction terms come in pairs:

  • Superior (towards the head) and inferior (towards the feet).
  • Anterior or ventral (towards the front) and posterior or dorsal (towards the back).
  • Medial (towards the midline of the body) and lateral (away from the midline).
  • Proximal (closer to where a limb attaches to the trunk) and distal (further away). These two are used for limbs.
  • Superficial (closer to the skin) and deep (further inside).

Three planes cut the body. The sagittal plane divides it into left and right parts. The coronal (frontal) plane divides it into front and back. The transverse (axial) plane divides it into upper and lower parts.

In the anatomical position the thumb points away from the body. So the radius, the forearm bone on the thumb side, is lateral, and the ulna is medial.

Self-check Compared with the elbow, where is the wrist?
  1. Deep
  2. Distal
  3. Proximal
  4. Superior

Answer: Distal. The wrist is further from where the arm attaches to the trunk, so it is distal. Proximal is the opposite direction, and in the anatomical position the wrist is below the elbow, so it is inferior, not superior.

3The main systems at a glance

Skeleton and joints. An adult has about 206 bones. The femur (thigh bone) is the longest; the ossicles of the middle ear are the smallest.

  • The spine has 7 cervical, 12 thoracic and 5 lumbar vertebrae, then the sacrum (5 fused vertebrae) and the coccyx.
  • There are 12 pairs of ribs, one pair for each thoracic vertebra. The breastbone is the sternum; the collarbone is the clavicle.
  • In a synovial joint the bone ends move freely. The hip and shoulder are ball-and-socket joints; the elbow and knee are hinge joints.

Muscles. A tendon attaches muscle to bone. A ligament connects bone to bone. There are three kinds of muscle tissue:

  • Skeletal muscle: striated (striped) and voluntary. It moves the skeleton.
  • Cardiac muscle: striated and involuntary. It is found only in the heart.
  • Smooth muscle: not striated and involuntary. It lines the gut, blood vessels and bladder.

Heart and vessels. The heart has four chambers: two atria on top that receive blood and two ventricles below that pump it out. Arteries carry blood away from the heart; veins carry blood back to it.

Nervous system. The central nervous system is the brain and the spinal cord. Twelve pairs of cranial nerves and 31 pairs of spinal nerves form most of the peripheral nervous system.

  • The cerebrum is the largest part of the brain. Its occipital lobe holds the primary visual cortex.
  • The cerebellum coordinates movement and balance. The medulla, in the brainstem, holds the centres for breathing and heart rate.
  • In an adult the spinal cord ends at about the level of vertebrae L1–L2.

Breathing and digestion. The diaphragm is the main muscle of breathing. The right lung has three lobes and the left lung has two. The liver makes bile and the gallbladder stores it.

Self-check Which type of muscle tissue is striated and involuntary?
  1. All three types
  2. Cardiac muscle
  3. Skeletal muscle
  4. Smooth muscle

Answer: Cardiac muscle. Cardiac muscle is striped like skeletal muscle but works without conscious control. Skeletal muscle is striated but voluntary; smooth muscle is involuntary but not striated.

4How to work out an anatomy question

Anatomy questions reward a fixed way of thinking more than memorising lists. Use these steps:

  1. Place the structure: which region of the body and which system it belongs to.
  2. Translate the words. Many names describe the part: “cost-” is rib, “hepat-” is liver, “nephr-” is kidney, “pulmon-” is lung.
  3. Recall the relations: what the structure is attached to, what supplies it with blood or nerves, what lies next to it.
  4. For a route (blood, urine, a nerve signal), trace it one stage at a time and say each stage aloud.
  5. For an injury case, ask what the damaged structure normally does. The loss of that job is the symptom.
  6. Remove options from the wrong region or the wrong system first, then choose between the rest.

Example of step 5: the radial nerve supplies the muscles that extend the wrist. Damage to it after a fracture of the humerus shaft causes “wrist drop”.

5A worked example

Trace the route one stage at a time. Try to name the next stage before you open it.

Worked example

Blood from the right arm returns to the heart in the superior vena cava. Which chambers and valves does it pass, in order, before it reaches the aorta?

1

Where the blood enters

Both venae cavae empty into the right atrium. This blood is low in oxygen (deoxygenated), because the arm has used the oxygen.

2

Into the right ventricle

From the right atrium the blood passes the tricuspid valve into the right ventricle.

3

To the lungs

The right ventricle pumps the blood through the pulmonary valve into the pulmonary trunk and the pulmonary arteries, which lead to the lungs.

These arteries carry deoxygenated blood. They are arteries because they carry blood away from the heart.

4

Back to the left side

In the lung capillaries the blood picks up oxygen. The pulmonary veins bring it to the left atrium.

5

Out to the body

The blood passes the mitral (bicuspid) valve into the left ventricle. The left ventricle has the thickest wall and pumps the blood through the aortic valve into the aorta.

6

Check the answer

Each side has one atrium, one valve, one ventricle, then one more valve. Every vessel that leaves a ventricle is an artery. The route fits both rules.

Answer

Right atrium → tricuspid valve → right ventricle → pulmonary valve → lungs → left atrium → mitral valve → left ventricle → aortic valve → aorta.

6Common mistakes

  • Thinking that arteries always carry oxygen-rich blood. The pulmonary arteries carry deoxygenated blood; the pulmonary veins carry oxygenated blood.
  • Mixing up tendons (muscle to bone) and ligaments (bone to bone).
  • Using your own left and right instead of the patient’s.
  • Mixing up the cerebrum (thinking, senses, voluntary movement) and the cerebellum (coordination and balance).
  • Saying the gallbladder makes bile. The liver makes it; the gallbladder stores and concentrates it.
  • Forgetting the anatomical position: palms face forward, so the radius is lateral.
Self-check Which vessel carries deoxygenated blood?
  1. A coronary artery
  2. A pulmonary vein
  3. The aorta
  4. The pulmonary artery

Answer: The pulmonary artery. The pulmonary artery takes blood from the right ventricle to the lungs to collect oxygen. Choosing a pulmonary vein comes from the rule “veins carry deoxygenated blood”, which is false for the lung circulation.

7How exam questions look

  • Easy (key terms and facts): names, locations and numbers. For example the longest bone, the number of rib pairs, or what “proximal” means.
  • Medium (applying the concepts): relations between structures. Which nerve supplies a muscle, which valve lies between two chambers, which vessel you use for a pulse.
  • Hard (cases and analysis): a short clinical case. You link an injury, a lesion or a symptom to the structure involved, such as a nerve injury after a fracture or the coronary artery behind an infarct.

For hard cases, ask what the structure normally does and where it runs. The symptom is almost always the loss of that function, below or beyond the point of damage.

Learn it step by step in the appLearn it step by step in the app

Example questions

Example 1Easy

Which flap of tissue covers the entrance to the larynx during swallowing?

  1. AUvula
  2. BVocal cords
  3. CSoft palate
  4. DEpiglottis
Show hints
  1. It is a leaf-shaped flap of elastic cartilage behind the root of the tongue.
  2. Two wrong answers are now crossed out. One of the remaining two is right.
Show the answer and explanation

Why this is the answer

The epiglottis folds back over the laryngeal inlet when you swallow, guiding food into the oesophagus instead of the airway.

Answer

D · Epiglottis
Example 2Medium

In which part of the nephron does most reabsorption of water and sodium take place?

  1. ADistal convoluted tubule
  2. BLoop of Henle
  3. CCollecting duct
  4. DProximal convoluted tubule
Show hints
  1. It is the first segment after Bowman's capsule.
  2. Two wrong answers are now crossed out. One of the remaining two is right.
Show the answer and explanation

Why this is the answer

The proximal convoluted tubule reabsorbs about two thirds of the filtered sodium and water, plus nearly all glucose and amino acids.

Answer

D · Proximal convoluted tubule
Example 3Hard

After an injury at the medial epicondyle of the elbow, a patient has numbness of the little finger and weakness of finger abduction. Which nerve is affected?

  1. AMusculocutaneous nerve
  2. BUlnar nerve
  3. CMedian nerve
  4. DRadial nerve
Show hints
  1. This is the "funny bone" nerve.
  2. Two wrong answers are now crossed out. One of the remaining two is right.
Show the answer and explanation

Why this is the answer

The ulnar nerve passes behind the medial epicondyle. It supplies most intrinsic hand muscles, including the interossei, and the skin of the little finger.

Answer

B · Ulnar nerve

Questions and answers

What is Human anatomy?

Doctors, nurses and therapists use anatomy every day. To give an injection, feel a pulse or understand an injury, you need to know exactly what lies under the skin at that spot.

The body is built in levels. Each level is made of the one below it:

How do I learn Human anatomy step by step?
  1. What anatomy is and why it matters
  2. The anatomical position and directions
  3. The main systems at a glance
  4. How to work out an anatomy question
  5. A worked example
  6. Common mistakes
  7. How exam questions look
What do the Human anatomy exercises cover?
  • Easy: key terms and facts
  • Medium: applying the concepts
  • Hard: cases and analysis

Every question has four options, and only one is right. Stuck? Open a small hint first, and the full explanation only when you need it.

How practising works

  • Every question has four options, and only one is right.
  • Stuck? Open a small hint first, and the full explanation only when you need it.
  • Your progress, mistakes and saved problems are kept, so you can review before the exam.

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